Research in my group addresses systemic and cellular consequences of changes in intracellular calcium levels in animals. We are specifcally interested in the second messenger Inositol 1,4,5-trisphosphate (InsP3) and its receptor – the InsP3 receptor. This protein exists on the membranes of intracellular calcium stores and performs the dual function of a receptor for InsP3 and a channel for calcium release. We address InsP3 receptor function in the model organism Drosophila using genetic, molecular, cellular, electrophysiological and behavioral methods.

Links to new stories about our recent work:

Calcium’s the key

Not just bones, brain too needs calcium.

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Calcium responses in dissociated neurons obtained from brains of Drosophila larvae.