We are interested in studying the cellular and molecular mechanisms those drive the formation of a special artery sub-type called collateral arteries. These collateral arteries, when present in the heart can save lives during coronary occlusions and consequently, facilitate heart regeneration. But how they are formed is unknown. We use genetic lineage tracing, experimental injury mouse models, confocal imaging and cardiac functional assays to understand the complex process of heart regeneration and the contribution of artery cells to it.