Prof. R. Sowdhamini - News
Soumya Nayak and Vikas Tiwari from the GS-2017 batch have joined our lab as PhD candidates. Binnu Gangadharan and Farah Haque from Prof. John Mercer's lab at inSTEM have joined our lab as bridging postdoctoral fellows. CAPS group extends a warm welcome to all! (Dec 2017/ Jan 2018)
Harini K, Meenakshi Iyer, Pankaj Chauhan and Shafi Kallayi presented posters at the Annual Talks at NCBS from January 3rd to 5th, 2018.
Pankaj Chauhan participated in the Indian Conference on Bioinformatics (InBIX'17 conference) organized by the Birla Institute of Scientific research and Bioclues.org at Jaipur between November 7-9, 2017. His work was also selected to be presented in the form of a short video abstract.
Bhavika Mam, Meenakshi Iyer, Neha Kalmankar and Teerna Bhattacharyya presented posters at the conference 'Structure Across Scales' in NCBS, Bangalore. October 7-8, 2017
Shaik Naseer Pasha has secured the DBT-MRC joint postdoctoral fellowship with Prof. R. Sowdhamini at NCBS and Dr. Carla Martins at the MRC Cancer unit at Cambridge. October 1st, 2017. Congratulations and we hope to see more amazing work in the future as well!
Bhavika Mam participated in the BC2 conference hosted by the Swiss Institute of Bioinformatics at Basel, Switzerland. Sepember 12-15, 2017
Snehal Karpe and colleagues have published an interesting study on odorant receptors in bees with implications in eusocial behavior: Scientific Reports 7: 10823 (2017). The paper can be accessed here: Computational genome-wide survey of odorant receptors from two solitary bees Dufourea novaeangliae (Hymenoptera: Halictidae) and Habropoda laboriosa (Hymenoptera: Apidae)
Pritha Ghosh secured a post-doctoral fellowship in the lab of Prof. Janusz Bujnicki at the International Institute of Molecular and Cell Biology, Warsaw, Poland. October, 2017. Congratulations and wish you success in future endeavours!
A study on RNA-binding proteins titled Bioinformatics comparisons of RNA-binding proteins of pathogenic and non-pathogenic Escherichia coli strains reveal novel virulence factors by Pritha Ghosh and R. Sowdhamini is now out: BMC Genomics
Mahita Jarjapu successfully defended her Ph.D. thesis, submitted to the Tata Institute of Fundamental Research, on 18th of August, 2017. Congratulations, Dr. Mahita Jarjapu! Her thesis seminar was on "Insights into Toll/interleukin-1 receptor (TIR) domain-mediated protein-protein interactions within the Toll-like receptor signalling pathway through computational approaches". Mahita's courage, hard-work, talent and persistence have been most inspiring to us all. Mahita has received bridging Postdoctoral Fellowship from NCBS and continues to work on some exciting projects in our lab!
A study co-authored by Mahita Jarjapu and R. Sowdhamini on the Integrative modelling of TIR domain-containing adaptor molecule inducing interferon-Î² (TRIF) provides insights into its auto-inhibited state is now out: Biology Direct 12:9 (2017)
Neha Kalmankar won the Best poster award for presenting her ongoing thesis work in the DST-SERB School of Chemical Ecology, 2017. Way to go, Neha! Congratulations! :)
Dr. Pritha Ghosh and Teerna Bhattacharyya were selected to participate in the Annual Symposium of the Indian Biophysical Society hosted at IISER Mohali from the 23rd to the 25th March, 2017. Pritha was invited to give a short twelve-minute talk as part of the Young Researchers Talk segment where she presented on A tale of two paralogs: Human Transformer2 proteins with differential RNA-binding affinities. Meanwhile, Teerna had been selected to present some of her thesis work as part of a poster titled Sequence and Structural Analysis of Gene Products containing Tyrosine Phosphatase Domain. It was an interesting experience for them both!
Mahita Jarjapu was among the five awardees of the Keystone Symposium Future of Science Scholarship to attend the Keystone Symposium Conference on Pattern Recognition Signalling:From Innate Immunity to Inflammatory Diseases at Banff, Canada from 19th to 23rd March, 2017.
In recognition of her scientific work impacting crop sciences thus helping farmers globally, Prof. Sowdhamini has been nominated as a "Food Hero" by CropLife International and Dr. Khader Shameer. The interview has been published here and the nominee profiles may be viewed here, March 2017. Congratulations! You are our hero too! :)
Prof. Sowdhamini and Prof. Srinivasan gave talks in SBCADD '17 held in Alagappa University, Karaikudi between 14th and 17th February 2017.
Shaik Naseer Pasha successfully defended his Ph.D. thesis, submitted to Manipal University, on 9th February, 2017. Congratulations, Dr. Shaik Naseer Pasha! You too have made us very proud! Naseer joins as a postdoctoral fellow in Dr. Dhandapany Perundurai's lab at InStem.
Prof. Sowdhamini and Prof. Srinivasan gave talks in the National Conference on Computational Analysis of Molecular Data in Synergy with Biological Applications (CAMB-2017) held at Bishop Heber College, Trichy on 3rd February 2017.
Pritha Ghosh successfully defended her Ph.D. thesis, submitted to the Tata Institute of Fundamental Research, on 25th January, 2017. Congratulations, Dr. Pritha Ghosh! You have made us very proud! Pritha has received bridging Postdoctoral Fellowship from NCBS and will continue to work on some more exciting work in our lab!
The review centred on protein-protein complexes and super hotspots is now out! To find out more, please read it here- "Specificity and stability of transient protein–protein interactions" Online: 11th January, 2017
Dr. Kaushik Hatti, who submitted his Ph.D. thesis to the Molecular Biophysics Unit (MBU), IISc has joined our lab starting 2nd of January, 2016! Welcome Kaushik!!
Prof. Sowdhamini delivered a highly lauded talk to the student crowd on the 3rd of December at the DHR-sponsored Training Program on Drug Chemistry held between November 15th to December 14th, 2016 at the JSS College of Pharmacy, Mysore. It was very well-received and extremely appreciated!
Meenakshi Iyer attended the "National Symposium on Bioinformatics and Computational Systems Biology" held at Central University of Himachal Pradesh, Shahpur from November 12-14, 2016. She also gave a flash talk and presented a poster on "Search of sequence homologues and update of the GenDiS database".
Pritha Ghosh submitted her thesis towards Ph.D. to the Tata Institute of Fundamental Research on the 21st of October 2016!
Oommen Kaleeckal Mathew submitted his thesis towards Ph.D. to SASTRA University on the 8th of November, 2016!
The paper titled "RStrucFam: a web server to associate structure and cognate RNA for RNA-binding proteins from sequence information" got published online on the 7th of October 2016. https://www.ncbi.nlm.nih.gov/
Anshul Sukhwal submitted his thesis towards Ph.D. to SASTRA University on 4th October 2016!
Naseer Pasha submitted his thesis towards Ph.D. to Manipal University on 27th September 2016!
Snehal Karpe presented a short talk as well as a poster titled "Identifying odorant receptor multi-protein superfamily from Apis florea genome" at the prestigious International Conference on Bioinformatics (InCoB2016) in Singapore held between the 21st to the 23rd of September 2016. Snehal won the Bronze award for the poster! She was funded by Prof. Sowdhamini and also won a partial travel grant from many sources including the organizers of the conference APBionet (Asia-Pacific Bioinformatics Network) and CICS (The Centre for International Co-operation in Science). Congratulations, Snehal!
Atul Upadhyay successfully defended his Ph.D thesis, submitted to the Tata Institute of Fundamental Research, on 23rd December, 2015. Congratulations, Dr. Atul Upadhayay!
Lab Alumnus Khader Shameer awarded BIRD Award, 2015
Khader Shameer, an alumnus of the lab, was awarded the Bioclues Innovation, Research and Development (BIRD) Award for the yer 2015 for his outstanding contribution to the area of Functional Genomics and Bioinformatics.
Research work on sequencing of lab Tulsi genome covered in news and news channels
The research conducted in a joint project involving researchers from the lab as well as certain researchers of the Bangalore BioCluster leading towards the sequencing of the Tulsi genome and unraveling its medicinal properties was covered by The Hindu newspaper.
The link to the news article can be found here.
NCBS webpage online:
Times of India:
Press club of India:
NDTV (September 9, 2015)
Titled: Indian Scientists Map Genome of Tulsi Plant
By: Pallava Bagla
in News Channels:
INDIATV (September 21, 2015)
Thesis defense by K.Harini
K.Harini was successful in defending her Ph.D thesis held on the 3rd June, 2015 in the NCBS campus.
From Ms. Margaret Sunitha to Dr. Margaret Sunitha
Margaret Sunitha, fondly known as Maggie, successfully defended her Ph.D thesis on 17th March, 2015.
Successful Ph.D thesis defence by Prashant Shingate
Prashant Shingate successfully defended his Ph.D thesis, submitted to Manipal University, on 30th January,2015.
Mahita Jarjapu awarded one of the NCBS Best Poster Prize
Mahita was awarded with one of the NCBS Best Poster Prizes during the NCBS Annual Talks, the theme of the talks being "Biology Across Scales", held from 5th to 8th January,2015.
Sony Malhotra successfully defends Ph.D thesis
Sony Malhotra successfully defended her Ph.D thesis, submitted to the Tata Institute of Fundamental Research, Mumbai, on 9th December, 2014.
Ph.D thesis defence by Eshita Mutt
Eshita successfully defended her Ph.D thesis, submitted to the International Institute of Information Technology (IIIT),Hyderabad on 6th November, 2014.
Two Ph.D students successfully submit doctoral thesis
Harini Krishnan and Margaret Sunita have submitted their Ph.D thesis to Bharathidasan University,Trichy, Tamil Nadu on June 27th, 2014.
Gandhimathi defends her Ph.D thesis
Gandhimathi successfully defended her Ph.D Thesis, submitted to Bharathidasan University, Trichy, Tamil Nadu, in March 2014.
Ph.D thesis defence by Swati Kaushik
Swati Kaushik successfully defended her Ph.D thesis,submitted to the Tata Institute of Fundamental Research (TIFR Deemed University), Mumbai on 30th January, 2014.
Pritha Ghosh awarded DAAD fellowship
Pritha Ghosh was awarded with the DAAD - A New Passage to India fellowship (2013) to work at Dr. Stefan Juranek's laboratory at the Department of Biochemistry, Universität Würzburg, Würzburg,Bavaria, Germany on a collobarative project involving RNA-binding proteins. An article in this regard can be found at the link here:
Reception for the guests from India. Persons shown in the photo: Upper row (from left): Alfred Forchel, Jürgen Kreft, Stefan Juranek and Andre Jäger. In front of them (standing): Pritha Ghosh, Subham Pandey and Sudarshan Kumar Kenettinkara. Lower row: Christian Klingenberg, Ajay Kumar Kolo, Ngaimuanching, Vijaya Sree Dondappagari and Stephan Schröder-Köhne. (Photo: Gunnar Bartsch)
Gandhimathi wins Best Poster Award
Gandhimathi won the second place in Best Poster Award for a poster entitled "structure-based virtual screening and evolutionary analysis for the identification of small molecule inhibitors to abrogate protein-protein interactions and paracrine Hedgehog signalling" during the International Conference on Recent Advances in Computational Drug Design organized by Schrodinger held on 16-17th Sep 2013.
Mahantesha submits Ph.D Thesis
Mahantesha successfully submitted his Ph.D thesis to the University of Agricultural Sciences,Bangalore on 16th September, 2013.
Research study leads towards the discovery of new odorant-binding proteins
A research study done by Prof. Sowdhamini and one of her Ph.D students, Malini Manoharan, in collobaration with Prof. Bernard Offman at the Université de la Réunion has led to the discovery of 110 new odorant-binding proteins in the genomes of three disease-transmitting mosquitoes:Anopheles gambiae,Aedes aegypti and Culex quinquefasciatus which are carriers of major human diseases like malaria,filariasis and chikungunya. The link to the news item covered by NCBS news can be found here:
NCBS-inSTEM team work that reveals structure adopted by tropomyosin contributes towards a better understanding of cardiomyopathies
Prof. Sowdhamini, along with her Ph.D student Margaret Sunita and a team of inSTEM researchers-Jim Spudich and John.A.Mercer have utilized findings from both experimental and theoretical studies to construct a detailed structural model of the tropomyosin in its so-called “open” position. This work has helped shed light on how the fourteen types of tropomyosin mutations can lead to the two types of cardiomyopathy-HCM (Hypertropic cardiomyopathy) and DCM (Dilated cardiomyopathy).NCBS news has covered this research study. http://news.ncbs.res.in/story/overcharged-heart
Thesis submission by B. Nagarathnam
Nagarathnam submitted her Ph.D thesis to Anna University, Chennai on 21st June, 2012.
Making the study of malformed proteins easy: Team of six construct database of 3D domain-swapped proteins
Prof. Sowdhamini along with her team of researchers-Shameer Khader, Prashant Shingate, S.C.P.Manjunath, M.Kartika and Ganesh Pugalenthi have successfully developed a database of 3D domain-swapped proteins, called 3DSwap after going through an intensive analysis including literature mining through hundreds of abstracts and scientific papers. During instances where 3D domain swapping can go wrong, it can lead to malfunctioning of proteins and result in protein aggregation and diseases like Alzheimers. The database, during its implementation contained 293 proteins that undergo 3D domain swapping. This makes it a lot easier for researchers working on Alzhemiers and other related diseases to find information at one place instead of having to search through literature. http://news.ncbs.res.in/story/swapping-long-drawn-data-searches-ingenuity-3dswap
Ganesh Pugalenthi wins BIRD Award 2011
Ganesh Pugalenthi won the Bioclues Innovation, Research and Development (BIRD) Award for the year 2011, awarded by Bioclues, a non-profit virtual organisation, for his work on the development of bioinformatic tools such as DIAL, SMotif,SPRED and ScanMot to anlayze protein sequences, structures and next-generation sequencing data, in the light of more and more databases being developed accompanied by an ever-increasing amount of data.
Research paper on 5-HT2A receptor receives Best Computer Aided and Molecular Design Award from VLife sciences, Pune
The research paper covering the work on the modelling and docking studies of 5-HT2A receptor done by doctoral students K. Kanagarajadurai, Malini Manoharan , Aditi Bhattacharya and Principal Investigators, Prof.Mitradas Panicker and Prof. Sowdhamini received the Best Research Publication Award 2011 in the field of Computet Aided and Molecular Design.http://news.ncbs.res.in/page/news-snippets
Shameer Khader wins 1st place in Eily Lilly and Company Outstanding Thesis Award Shameer Khader won the 1st place in the Eily Lilly and Company Outstanding Thesis Awards for his doctoral thesis titled “Identification and analysis of domains in proteins”.http://news.ncbs.res.in/page/news-snippets
Prof. R. Sowdhamini receives Bharat Jyoti Award and Glory of India Gold Medal Prof. Sowdhamini has received the Bharat Jyoti Award from the International Friendship Society and the Glory of India
Gold Medal from the Institute of Success Awareness for the year 2011.
Prof. R. Sowdhamini elected as a Fellow of IAS and INSA
Prof. Sowdhamini was elected as a fellow to the Indian Academy of Sciences (IAS),Bangalore in January
2010.Subsequently she was elected as a fellow to the Indian National Science Academy (INSA), in December 2010.
Prof. Sowdhamini with her certificate from the INSA
Prof. Sowdhamini awarded HFSP Grant
Prof.R. Sowdhamini was appointed as the Principal Investigator for a project involving an interdisciplinary approach, employing bioinformatics, experimental biochemistry-biophysics and mathematical modelling. This award is special as it is the first HFSP programme grant where an Indian researcher is a Principal Investigator. This grant will be used to fund a research work on a group of mechanosensory proteins called myosins carried out between the labs of Prof R. Sowdhamini, Prof. James Spudich (Stanford University, USA) and Prof.Henrik Flyvbjerg (Technical University of Denmark).
Prof. Sowdhamini receives Young Woman Career Scientist Award
Prof. Sowdhamini was awarded the Young Woman Career Scientist Award by the Department of Biotechnology
(DBT), Govt. Of India on 12th April, 2007.
Prof. Sowdhamini receiving the Young Women Career Scientist Award