For PDFs of papers, please write to us.

(*Equal contribution; Lab members)

Sane M, Diwan GD, Bhat BA, Wahl LM and Agashe D (2023). Shifts in mutation spectra enhance access to beneficial mutations. Proceedings of the National Academy of Science 120:e2207355120 | Preprint | Online access | NCBS news article

Raval PK, Ngan WY, Gallie J and Agashe D (2023). The layered costs and benefits of translational redundancy. eLife 12:e81005 Open Access | eLife Digest | Press release

Ravi Kumar V, Agavekar G and Agashe D (2023). Fitness landscapes reveal context-dependent benefits of oviposition behavior. Evolution 77(2):550–561 Open Access

Wortel M, Agashe D, …. and Pennings P [total 36 authors] (2023). Towards evolutionary predictions: current promises and challenges. Evolutionary Applications 16(1):3–21 Open Access

Sanjenbam P, Shivaprasad PV and Agashe D (2022). Impact of phyllosphere Methylobacterium on host rice landraces. Microbiology Spectrum 10(4):e00810-22 Open access

Agashe D (2022). The evolutionary impacts of synonymous mutations. In: Sauna Z and Kimchi-Sarfaty C (eds). Single Nucleotide Polymorphisms. Springer, Cham. Preprint | Online Access

Mahajan S and Agashe D (2022). Evolutionary jumps in bacterial GC content. G3|Genes|Genomes|Genetics 12:jkac108. Preprint | Online access | Research Matters article

Wahl LM and Agashe D (2022). Selection bias in mutation accumulation. Evolution 76: 528-540 Online Access | NCBS news article

Agashe D, Maheshwary S,…, Roy Chaudhuri C, Devi P [total 13 authors] (2022). Career challenges for young independent researchers in India. Current Science 122:143 Online access

Prakash A, Agashe D and Khan I (2022). The costs and benefits of basal infection resistance vs immune priming responses in an insect. Developmental and Comparative Immunology 126:104261 Online access | Preprint

Samhita L, Raval PK*, Stephenson G*, Thutupalli S and Agashe D (2021). The impact of mistranslation on phenotypic variability and fitness. Evolution 75(5):1201-1217

Agarwal A and Agashe D (2020). The red flour beetle Tribolium castaneum: A model for host-microbiome interactions. PLoS One 15(10): e0239051

Joshi S and Agashe D (2020). Ontogenic color change, survival, and mating in the damselfly Agriocnemis pygmaea Rambur (Insecta: Odonata). Ecological Entomology 45: 1015-1024

Samhita L, Raval PK and Agashe D (2020). Global mistranslation increases cell survival under stress in E. coli. PLoS Genetics 16(3): e1008654

Sanjenbam P, Buddidathi R, Venkatesan R, Shivaprasad PV and Agashe D (2020). Phenotypic diversity of Methylobacterium associated with rice landraces in North-east India. PLoS One 15(2): e0228550

Phalnikar K, Kunte K and Agashe D (2019). Disrupting butterfly microbiomes does not affect host survival and development. Proceedings of the Royal Society of London B 286:20192438 

Deb R, Nair A and Agashe D (2019). Host dietary specialization and neutral assembly shape gut bacterial communities of wild dragonflies. PeerJ 7:e8058

Khan I, Prakash A and Agashe D (2019). Pathogen susceptibility and fitness costs explain variation in immune priming across natural populations of flour beetles. Journal of Animal Ecology 88(9): 1332-1342

Kaminski Strauss S, …, Agashe D, …, Walunjkar N, …. and Yitzak Pilpel* [total 63 authors] (2019). Evolthon: A community endeavor to evolve lab evolution. PLoS Biology 17(3): e3000182

Agavekar G, Agashe D and Economo EP (2019). Dimensions of ant diversity on a small tropical island. Insect conservation and diversity 12: 161-171

Kumar VR, Issar S and Agashe D (2018). The induction of larval resource preference in heterogeneous habitats. Ecological Entomology 43, 719–730

Sane M, Miranda JJ and Agashe D (2018). Antagonistic pleiotropy for carbon use is rare in new mutations. Evolution 72(10):2202-2213

Diwan GD and Agashe D (2018). Wobbling forth and drifting back: The evolutionary history and impact of tRNA modifying enzymes. Molecular Biology and Evolution 35(8):2046-2059

Phalnikar K, Kunte K and Agashe D (2018). Dietary and developmental shifts in butterfly-associated bacterial communities. Royal Society Open Science 5:171559

Agashe D and Kunte K [editors] (2018). Special issue on the Genetics of Adaptation, based on the symposium of the same name, held at NCBS in Nov-Dec 2016. Molecular Biology and Evolution Virtual Issue

Khan I, Prakash A, Issar S, Umarani M, Sasidharan R, Masagalli JN, Lama P, Venkatesan R and Agashe D (2018). Female chemical warfare drives fitness effects of group sex ratio. American Naturalist

Mahajan S and Agashe D (2018). Translational selection for speed is not sufficient to explain variation in bacterial codon usage bias. Genome Biology and Evolution 10(2):562–576

Khan I*, Prakash A* and Agashe D (2017). Experimental evolution of insect immune memory vs. pathogen resistance. Proceedings of the Royal Society of London B 284: 20171583

Agashe D (2017). The road not taken: Could stress-specific mutations lead to different evolutionary paths? PLoS Biology 15(6): e2002862

Khan I, Agashe D and Rolff J (2017). Early life inflammation, immune response and aging. Proceedings of the Royal Society of London B 284: 20170125

Diwan GD and Agashe D (2016). The frequency of internal Shine-Dalgarno – like motifs in prokaryotes. Genome Biology and Evolution 8(6):1722-1733

Khan I*, Prakash A* and Agashe D (2016). Divergent immune priming responses across life stages and populations of flour beetles. Ecology and Evolution 6: 7847–7855

Nayak DD, Agashe D, Lee M-C, and Marx CJ (2016). Selection maintains apparently degenerate metabolic pathways due to tradeoffs in using methylamine for carbon versus nitrogen. Current Biology 26:1416-1426

Agashe D, Sane M*, Phalnikar K*, Diwan GD*, Habibullah A, Martinez-Gomez NC, Sahasrabuddhe V, Polachek W, Wang J, Chubiz L and Marx CJ (2016). Large-effect beneficial synonymous mutations mediate rapid and parallel adaptation in a bacterium. Molecular Biology and Evolution 33:1542-1553

Nair A and Agashe D (2016). Host-specific, spatial and temporal variation in culturable gut bacterial communities of dragonflies. Current Science 110(8):1513-1523 

Khan I, Prakash A and Agashe D (2016). Immunosenescence and the ability to survive bacterial infection in the red flour beetle Tribolium castaneum. Journal of Animal Ecology 85: 291-301

Kunte K and Agashe D [guest editors] (2015). Special section on Evolutionary Biology, in Current Science 108:1835-1873

Carroll SM, Chubiz LM, Agashe D and Marx CJ (2015). Parallel and divergent evolutionary solutions for the optimization of an engineered central metabolism in Methylobacterium extorquens AM1. Microorganisms 3:152-174

Parent CE*, Agashe D* and Bolnick DI (2014). Intraspecific competition reduces niche width in experimental populations. Ecology and Evolution 4(20): 3878-3990

Agashe D and Shankar N (2014). The evolution of bacterial DNA base composition. Journal of Experimental Zoology B 322(7): 517-528

Selected prior publications

Agashe D, Martinez-Gomez NC, Drummond DA and Marx CJ (2013). Good codons, bad transcript: large reductions in gene expression and fitness arising from synonymous mutations in an a key enzyme. Molecular Biology and Evolution 30(3): 549-560.

Agashe D, Falk JJ and Bolnick DI (2011). Effects of founding genetic variation on adaptation to a novel resource. Evolution 65(9): 2481-2491

Agashe D and Bolnick DI (2010). Intraspecific genetic variation and competition interact to facilitate niche expansion. Proceedings of the Royal Society of London, series B. 277(1696): 2915-2924

Agashe D (2009). The stabilizing effect of intraspecific genetic variation on population dynamics in novel and ancestral habitats. American Naturalist 174(2): 255-267.