TitlePathways of clathrin-independent endocytosis.
Publication TypeJournal Article
Year of Publication2007
AuthorsMayor S, Pagano RE
JournalNat Rev Mol Cell Biol
Date Published2007 Aug
KeywordsAnimals, Bacteria, Biological Transport, Active, Clathrin, Endocytosis, Eukaryotic Cells, Humans, Virus Internalization, Viruses

There are numerous ways that endocytic cargo molecules may be internalized from the surface of eukaryotic cells. In addition to the classical clathrin-dependent mechanism of endocytosis, several pathways that do not use a clathrin coat are emerging. These pathways transport a diverse array of cargoes and are sometimes hijacked by bacteria and viruses to gain access to the host cell. Here, we review our current understanding of various clathrin-independent mechanisms of endocytosis and propose a classification scheme to help organize the data in this complex and evolving field.

Alternate JournalNat. Rev. Mol. Cell Biol.
PubMed ID17609668
Grant List / / Wellcome Trust / United Kingdom