Dr. Varadharajan Sundaramurthy - Publications
Sachdeva K and Sundaramurthy V (2020) The Interplay of Host Lysosomes and Intracellular Pathogens. Front. Cell. Infect. Microbiol. 10:595502. doi: 10.3389/fcimb.2020.595502
Pradeep A. Subramani, Neha Vartak-Sharma, Seetha Sreekumar, Pallavi Mathur, Bhavana Nayer, Sushrut Dakhore, Sowmya K. Basavanna, Devaiah M. Kalappa, Ramya V. Krishnamurthy, Benudhar Mukhi, Priyasha Mishra, Noriko Yoshida, Susanta Kumar Ghosh, Radhakrishan Shandil, Shridhar Narayanan, Brice Campo, Kouichi Hasegawa, Anupkumar R. Anvikar, Neena Valecha & Varadharajan Sundaramurthy (2020). “Plasmodium vivax liver stage assay platforms using Indian clinical isolates”. Malaria J 19, 214 (2020). https://doi.org/10.1186/s12936-020-03284-8
Sachdeva, K., Goel, M., & Sundaramurthy, V. (2020). “Heterogeneity in the endocytic capacity of individual macrophage in a population determines its subsequent phagocytosis, infectivity and sub‐cellular trafficking”. Traffic. doi:10.1111/tra.12752
Kuldeep Sachdeva, Manisha Goel, Malvika Sudhakar, Mansi Mehta, Rajmani Raju, Karthik Raman, Amit Singh, Varadharajan Sundaramurthy (2020). “Mycobacterium tuberculosis (Mtb) lipid–mediated lysosomal rewiring in infected macrophages modulates intracellular Mtb trafficking and survival”. J. Biol. Chem. May 18, 2020. doi: 10.1074/jbc.RA120.012809
Balasubramanian L, Zuzarte-Luís V, Syed T, Mullick D, Deb S, Ranga-Prasad H, Meissner J, Almeida A, Furstenhaupt T, Siddiqi K, Prudêncio M, Rodrigues CMP, Mota M and Sundaramurthy V. (2020). “Association of Plasmodium berghei With the Apical Domain of Hepatocytes Is Necessary for the Parasite's Liver Stage Development”. Front. Cell. Infect. Microbiol. 9:451. doi: 10.3389/fcimb.2019.00451
Evans RJ, Sundaramurthy V and Frickel EM (2018). “The Interplay of Host Autophagy and Eukaryotic Pathogens”. Front. Cell Dev. Biol. 6:118. doi: 10.3389/fcell.2018.00118
Sundaramurthy V*, Korf H, Singla A, Scherr N, Nguyen L, Ferrari G, Landmann R, Huygen K, Pieters J. "Survival of Mycobacterium tuberculosis and Mycobacterium bovis BCG in lysosomes in vivo". Microbes Infect. 2017 Nov;19(11):515-526. 2017.
Sundaramurthy, V. Barsacchi, R. Chernykh, M. Stoter, M. Tomschke, N. Bickle, M. Kalaidzidis, Y. and Zerial, M. "Deducing the mechanism of action of compounds identified in phenotypic screens by integrating their multiparametric profiles with a reference genetic screen". Nature protocols, 9, 474-90, 2014.
Varadharajan Sundaramurthy, Rico Barsacchi, Nikolay Samusik, Giovanni Marsico, Jerome Gilleron, Inna Kalaidzidis, Felix Meyenhofer, Marc Bickle, Yannis Kalaidzidis and Marino Zerial. “Integration of chemical and genome-wide siRNA multi-parametric profiles identifies triggers of intracellular mycobacterial killing “. Cell Host and Microbe, 13, 129-142, February 13, 2013.
Rajesh Jayachandran*, Varadharajan Sundaramurthy*, Benoit Combaluzier, Philipp Muller, Hannelie Korf, Kris Huygen, Toru Miyazaki, Imke Albrecht, Jan Massner and Jean Pieters. "Survival of Mycobacteria in Macrophages is Mediated by Coronin 1 Dependent Activation of Calcineurin". Cell, 130, 37-50, July 13, 2007. (* equal contribution).
Varadharajan Sundaramurthy and Jean Pieters. "Interactions of pathogenic mycobacteria with host macrophages". Microbes and Infection, Nov-Dec;9(14-15):1671-9, 2007.
S. Varadharajan, B. K. Chandrasekhar Sagar, P. N. Rangarajan and G. Padmanaban. "Localization of Ferrochelatase in Plasmodium falciparum". Biochem. J. 384, 429-36, 2004.
S. Varadharajan, S. Dhanasekharan, Z. Q. Bonday, P. N. Rangarajan and G. Padmanaban. "Involvement of d-Aminolaevulinate synthase encoded by parasite gene in de novo haem synthesis by Plasmodium falciparum". Biochem. J. 367, 321-327, 2002.