Day-1 | 6 February 2023
13:00-16:00 Registration (outside inStem 150 seater auditorium)
15:00-16:00 Opening Welcome Reception - Tea/Coffee (inStem atrium)
16:00-16:15 Welcome Address Dr. Bhavana Muralidharan & Dr. Shubha Tole
Session 1: Cerebral organoids to study neurodevelopment
(Chair: Dr. Carol Schuurmans)
16:15-16:45  Brain organoids for modeling brain malformations: clues from the progenitors
                      Dr. Orly Reiner
16:45-17:15 Engineered human cortical spheroids for dissecting molecular determinants of neurodevelopment
                    Dr. Debojyoti Chakraborty
17:15-17:30 Dissecting the genetic determinants of cortical interneuron migration in human forebrain assembloids
                     Riya Rauthan
17:30-17:45 Take a breather - Short Break
Session 2: Biomedical Ethics
(Chair: Dr. Shubha Tole)
17:45-18:15 Foregrounding Equity, Justice and Inclusion as Determinants of Access to Precision Medicine: An Ethical Case Study of Patient-Derived Tissue Organoids
                    Dr. Ubaka Ogbogu
18:15-18:45 Ethical and social considerations of multi-system organoids: Need of interdisciplinary approaches
                    Dr. Kazuto Kato
18:45-19:30 Panel Discussion
                    Dr. Maneesha Inamdar, Dr. Ubaka Ogbogu, Dr. Kazuto Kato
19:30           Dinner (inStem Canteen First Floor)
Day-2 | 7 February 2023
8:00-9:00 Breakfast (NCBS Main canteen First floor)
Session 3: iPSC-derived 2D and 3D systems to model CNS disorders
(Chair: Dr. Orly Reiner)
09:00-09:30 Modelling neurodevelopmental disorders using iPSC-derived 2D neuronal cultures and 3D cerebral organoids
                    Dr. Bhavana Muralidharan
09:30-10:00 Patient-derived brain organoids to characterize epileptic Dravet syndrome
                    Dr. Deborah Kurrasch
10:00-10:30 Creating functional human cortical circuits in vivo using stem cells and implications for modeling neurodevelopmental disorders"
                     Dr. Omer Revah
10:30-11:00 Coffee break (inStem atrium)
11:00-11:30 Modeling neurodegenerative diseases using iPSC-derived neuronal and
                    glial cells
                    Dr. Stefano Stifani
11:30-12:00 Understanding eye development and disease using patient-specific iPSCs and iPSC-derived organoids
                     Dr. Indumathi Mariappan
12:00-13:00 Poster Blitz - Teasers
                     Dr. Orly Reiner
13:00-14:00 Lunch (inStem Canteen First Floor)
14:00-16:00 Poster Session 1 + Coffee break (inStem atrium)
                     Poster session and coffee? As quintessential as tea and biscuits.
Session 4: Mentoring Session
(Chair: Dr. Shubha Tole)
16:00-16:30 Navigating graduate school
                    Dr. Shubha Tole
16:30-17:00 How to choose a postdoc
                    Dr. Deborah Kurrasch
17:00-17:30 Work-life balance and mental health
                     Dr. Isabelle Aubert
17:30-18:00 Diversity and Inclusion
                     Dr. Shalini Arya
18:00-18:30 Stepwise: from a small town in India to a successful career
                     Dr. Nandini Trivedi (virtual)
18:30-19:30 Open Panel Discussion
                     Session speakers
19:30 Dinner and continued round table discussion (inStem Canteen First Floor)
21:00 Cultural Music Program (inStem 150 seater auditorium)
           The Science and magic in Indian classical music by Dr “Surprise”
Day-3 | 8 February 2023
8:00-9:00 Breakfast (NCBS Main canteen First floor)
Session 5: Organoid Bioengineering
(Chair: Dr. Bhavana Muralidharan)
9:00-9:30 Using machine learning and bioengineering to build robust human organoids
                 Dr. Sharad Ramanathan
09:30-10:00 Sensor-embedded 3D human organoids for drug development
                     Dr. Yaakov Nahmias
10:00-10:15 Efficient expansion of iPSC-derived human lung epithelium as adherent cultures and 3D organoids using defined, serum free medium for disease modelling and cell                             therapy
                    Swathi Narasimhaiah
10:15-10:30 MicroRNA-135 drives human neural stem cell fate determination: Employing induced pluripotent stem cells (iPSCs) derived 2D neural stemcells (NSCs)
                     Yogita Adlakha
10:30-11:00 Let’s get the elixir of success - It’s coffee time (inStem atrium)
11:00-11:30 A human stem-cell model of neural tube folding morphogenesis
                    Dr. Eyal Karzbrun
11:30-12:00 From personalized blood-brain-barrier (BBB)-on-Chip to pre-clinical BBB targeted gene therapy
                    Dr. Gad Vatine
12:00-12:15 How LIS1 is Involved in the Regulation of the Extracellular Matrix
                     Maayan Karlinski
12:15-13:15 Poster Blitz
                     Dr. Orly Reiner
13:15-14:15 Lunch (inStem Canteen First Floor)
14:15-16:15 Poster Session 2 + Coffee break (inStem atrium)
17:00-17:30 Departure Gala Dinner
18:00-21:00 Gala Dinner
21:00 Return to hotel
Day-4 | 9 February 2023
8:00-9:00 Breakfast (NCBS Main canteen First floor)
Session 6: Other tissue organoids
(Chair: Dr. Debojyoti Chakraborty)
9:00-9:30 Engineering organoids to understand human development and disease
                 Dr. Nuria Montserrat
09:30-10:00 Human organoid models of kidney disease and regeneration
                    Dr. Benjamin Freedman
10:00-10:15 Exploiting Intestinal Organoid Model to interrogate Shigella pathogenesis
                     Nidhi Kamboj
10:15-10:30 Establishing 3D multicellular spheroid to imitate tumor microenvironment for chemotherapeutic drug efficacy modulation in cancer
                    Khushwant Singh
11:00-11:30 Inherited pancreatic disorders illuminated by pluripotent stem cells
                    Dr. Markus Breunig
10:30-11:00 High tea (inStem atrium)
11:30-12:00 Modeling atrophy and metabolic disease using skeletal muscle organoids
                    Dr. Arvind Ramanathan
12:00-12:30 Organs-on-a-Chip: A new tool for studying physiology
                     Dr. Ben Maoz
12:30-12:45 Constitutive activation of canonical Wnt signaling disrupts choroid plexus
                     epithelial fate
                     Arpan Parichha
12:45-13:00 Unravelling the role of the ciliary protein CEP290 in neural development by generation of human 2D and 3D iPSC-derived neuronal models for the ciliopathy Joubert                             Syndrome
                     Melanie Eschment
13:00-14:00 Lunch (inStem Canteen First Floor)
Session 7: Modeling disease and neurodevelopment with cerebral organoids
(Chair: Dr. Indumathi Mariappan)
14:00-14:30 Modeling neurodevelopmental diseases and cancer using cerebral organoids
                     Dr. Pavithra Chavali (virtual)
14:30-15:00 Using brain organoids to interrogate proneural gene function
                     Dr. Carol Schuurmans
15:00-15:30 Modeling human brain development and disease: the role of primary cili
                    Dr. Christina Kyrousi
15:30-15:45 Adrenomedullin promotes interneuron migration in a human forebrain assembloid for hypoxic interneuronopathy of prematurity 
                     Dhriti Nagar
15:45-16:00 Dissecting the involvement of acid sphingomyelinase inhibition in GBA-dependent Parkinson’s disease
                     Silvia Breviario
Closing and Awards
Closing Remarks and Awards
Dr. Shubha Tole & Dr. Bhavana Muralidharan
High Tea (inStem atrium) & Departure
Venue for all the talks will be - inStem 150 seater auditorium