Protein sequences, sequence alignment; Basic polypeptide stereochemistry, hierarchy in protein folds: secondary structure, tertiary structure; Protein structure determination by X-ray crystallography. Principles of protein purification, crystallization, structure determination; Structure validation and best practices on the use of protein structures from the protein data bank; Protein fold-function relationships; RNA secondary structure prediction and covariation analysis; RNA secondary structure determination methods, RNA structure determination and dynamics by X-ray and NMR, RNA dynamics studies by other biophysical methods; Dynamics of Protein-RNA complexes; Structure and organisation of genomes; genome sequencing, assembly, annotation and functional genomics; gene expression and its regulation; chromosome topologies, their dependence on cellular states and their influence on gene expression. Protein functional dynamics, Protein dynamics studies by MD simulations; Basic NMR techniques, Protein dynamics by NMR; Protein dynamics studies by other biophysical techniques.