Model building, Refinement and Validation of data derived from Cryo-EM

28 July – 1 August 2025 | National Centre for Biological Sciences, TIFR, Bengaluru

Together with CCP-EM, UK, we are pleased to announce workshop on 'Model building, refinement and Validation of data derived from Cryo-EM'. The aim of the workshop is to provide hands-on training for PhD students and researchers at different career levels (post-doctoral fellows and faculty) in the field of conventional and AI-based approaches for automatic model building in Cryo-EM maps, model refinement and validation with a primer on efficient data collection and image processing. The workshop will provide a forum to highlight state of the art developments in computational cryo-EM and related themes as well as showcasing some recent biological applications. This course will host some of the leading software developers and provide ample contact time to allow participants to discuss their data in detail alongside traditional lectures and tutorials.  The workshop will cover advanced use of LocScale, ModelAngelo, findMySequence-checkMySequence, EM_placement, Coot/Moorhen, TEMPy-REFF, ISOLDE, Refmac-Servalcat, new validation tools and EMDB/PDBe developments.

The venue of the workshop is at the National Centre for Biological Sciences, TIFR, Bengaluru.  

Due to various constraints, we can only accommodate a maximum of 20 participants. Thus, we strongly encourage researchers who have already obtained cryo-EM maps and would like to learn the later steps of Model building, refinement and validation of the models. The participants should also bring their own laptop (and data), which can be used during the workshop.

Application

Interested applicants should send their CV, research interest including how this workshop will benefit their research. The CV and details should be sent to cryoemncbs@gmail.com.

The final date for the applications is May 7th, 2025 and the selected applicants will be notified by 1st week of June, 2025.

Registration Fees

Academic Researchers - 7,500 Rs.

Industrial Participants - 15,000 Rs.

Registration fees includes accommodation and food. Limited travel grant for student researchers might become available.

 

Confirmed workshop speakers/tutors

Randy Read, University of Cambridge

Garib Murshudov, MRC Laboratory of Molecular Biology, Cambridge

Maya Topf, Center for Structural Systems Biology (CSSB), Hamburg

Arjen Jakobi, Delft University of Technology, Delft

Lucrezia Catapano, MRC Laboratory of Molecular Biology, Cambridge

Tom Burnley, CCP-EM, STFC

Sony Malhotra, CCP-EM, STFC

Agnel Joseph, CCP-EM, STFC

Tom Mulvaney, Center for Structural Systems Biology (CSSB), Hamburg

Martyn Winn, CCP-EM, STFC

Shruthi Viswanath, NCBS

Saikat Chowdhury, CCMB

Madhusudhan, M.S, IISER, Pune

Online talks

Sjors Scheres, MRC Laboratory of Molecular Biology, Cambridge

Grigore Pintilie, Stanford University

Tristan Croll, Altos Labs, Cambridge

Kyle Morris, EBI, UK

Grzegorz Chojnowski, Center for Structural Systems Biology (CSSB), Hamburg

 

Preliminary Schedule

Modelling Workshop Schedule

 

Workshop organisers

Vinothkumar K.R. (NCBS, Bengaluru)

Somnath Dutta (IISc, Bengaluru)

Agnel Praveen Joseph, (CCP-EM, STFC, UK)

 

Sponsors

We would like to thank CCP-EM, STFC, UK, Department of Biotechnology, India