TitlePIMADb: A Database of Protein-Protein Interactions in Huge Macromolecular Assemblies.
Publication TypeJournal Article
Year of Publication2016
AuthorsMathew OK, Sowdhamini R
JournalBioinform Biol Insights
Volume10
Pagination105-9
Date Published2016
ISSN1177-9322
Abstract

Protein-protein interactions play a very important role in the process of cellular functionality. Intricate details about the interactions between the proteins in a macromolecular assembly are important to understand the function and significance of protein complexes. We are reporting about a database of protein-protein interactions in huge macromolecular assemblies (PIMADb) that records the intrinsic details of 189,532 interchain interactions in 40,049 complexes from the Protein Data Bank. These details include the results of the quantification and analysis of all the interactions in the complex. The availability of interprotomer interaction networks can enable the design of point mutation experiments. PIMADb can be accessed from the URL: http://caps.ncbs.res.in/pimadb.

DOI10.4137/BBI.S38416
Alternate JournalBioinform Biol Insights
PubMed ID27478368
PubMed Central IDPMC4954588