Design of ultrasensitive DNA-based fluorescent pH sensitive nanodevices.
| Title | Design of ultrasensitive DNA-based fluorescent pH sensitive nanodevices. |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Halder S, Krishnan Y |
| Journal | Nanoscale |
| Volume | 7 |
| Issue | 22 |
| Pagination | 10008-12 |
| Date Published | 2015 Jun 14 |
| ISSN | 2040-3372 |
| Abstract | Here we tune the pH sensitivity of a DNA-based conformational switch, called the I-switch, to yield a set of fluorescent pH sensitive nanodevices with a collective, expanded pH sensing regime from 5.3 to 7.5. The expanded pH regime of this new family of I-switches originates from a dramatic improvement in the overall percentage signal change in response to pH of these nanodevices. |
| DOI | 10.1039/c5nr01158b |
| Alternate Journal | Nanoscale |
| PubMed ID | 25990365 |
| Grant List | / / Wellcome Trust / United Kingdom |