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Introduction to Laboratory Practices [2009 Aug Term]
Instructors: SP Koushka, D Nair, U Ramakrishnan
Credits: 0 (Required)
Duration: Aug 4, 2009 – Aug 19, 2009
Schedule: TWRF 4:00PM – 6:00PM, Teaching Lab
Outline: Introduction to basic laboratory practices and techniques. Lab safety and etiquette. Maintaining lab notebooks.
Duration: Aug 24, 2009 – Dec 15, 2009
Schedule: MWF 9:00AM – 10:30AM, LH2
Outline: Structural organization of proteins, nucleic acids and membranes. Thermodynamics: the laws; biochemical thermodynamics; statistical thermodynamics; stabilizing interactions in biomolecules; thermodynamics of ion, electron and solute transport; association between molecules. Macromolecular dynamics: fluorescence methods; hydrogen exchange; biomolecular motors; kinetics; enzyme catalysis; mass spectrometry of biomolecules.
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Molecular Biology [2009 Aug Term]
Duration: Sep 1, 2009 – Nov 26, 2009
Schedule: TR 9:15AM – 10:15AM
Outline: Nucleic acid structure. The genetic code. Prokaryotic transcription and translation. DNA replication and recombination; mutations and repair. Eukaryotic transcription. Bioinformatics. RNAi/microRNA.
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Duration: Aug 26, 2009 –
Schedule: WF 2:00PM – 4:00PM
Outline: The course will aim to understand cell- fate specification and morphogenesis in animal and plant development from a mechanistic perspective. The latter means that there will be a attempt to develop a molecular- and cellular-understanding as opposed to a descriptive one.
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Instructor: M Thattai
Credits: 3 (Basic)
Duration: Aug 25, 2009 – Oct 29, 2009
Schedule: TR 2:00PM – 3:30PM, LH3
Instructor: E Lebow
Credits: 3 (Basic)
Duration: Aug 24, 2009 – Oct 28, 2009
Schedule: MW 2:00PM – 3:30PM, LH3; Tutorial: T 10:30AM – 11:30AM
Duration: Sep 1, 2009 – Oct 29, 2009
Schedule: TR, 10:30AM – 12:30PM, FFSH
Outline: Chemical biology of macromolecules. DNA and RNA structure. Control of gene expression. DNA replication. DNA damage and repair. RNA processing. Ribosomes and translation. RNA control of gene expression. Chemical sensors. Chemical genetics.
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Outline: An eight week course that aims to upgrade your scientific writing skills. Clear and logical prose. Text composition. Argument maps. Extracting arguments from a text.
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Duration: Jan 12, 2010 – April 17, 2010
Outline: The logic and techniques of genetic analysis; epistasis, suppressors, genetic interaction networks and reverse genetics and genomics. Illustration of the application of genetic analysis of specific pathways in model organisms of C. elegans, Drosophila, Yeast, bacteriophage and plants. Examples discussed include genetics of phage morphogenesis, bacterial chemotaxis, regulation of cell cycle, genome rearrangements, genetic recombination, transposition, signaling and developmental mechanisms, synapse formation and function.
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Outline: Cellular organization. Intracellular traffic. Motors and the cytoskeleton. Cell signalling. Chromatin structure. Organellar biogenesis. Cell cycle. Apoptosis.
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Duration: Jan 23, 2010 – Jan 28, 2010
Schedule: Meeting in Pondicherry
Outline: We discuss the following areas: molecular motors, the cytoskeleton, mitosis, principles of intracellular transport, biophysics of molecular motors, and modeling of intracellular transport. See workshop website for more information. Students interested in taking this as a course for credit please speak to Sandhya before December 15th, 2009.
Duration: Feb 1, 2010 – Apr 31, 2010
Outline: Philosophy of neuroscience. Neuronal physiology: Cable theory, voltage and ligand-gated channels, Ionic potentials and ionic currents. Computation with neurons: Dendritic and synaptic integration, voltage-gated channels and nonlinearities, integrate and fire neurons, neural coding. Synaptic signaling: biochemical basics, computing with chemicals, amplification, summation, temporal computation, bistability. Neuroanatomy: Brain regions and functions. Synaptic function and synaptic plasticity. Invertebrate neurons and networks. Medical implications.
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Duration: JAN 1, 2010 - Mid April 2010
Schedule: M 11:30AM - 1:00PM, LH2; WF 2:00PM - 3:30PM LH3;
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Outline: Leukemia as a system to familiarize basic scientists with research issues in the context of disease biology, covering the study of genetics and molecular biology, cytogenetics, hematological lineage analysis, drug discovery and related structural biology.
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Biomolecular Spectroscopy and Bioanalytical Chemistry [2010 Jan Term]
Credits: 3 (Basic)
Outline: The course will cover theoretical aspects and applications of modern techniques in spectroscopy and bioanalytical chemistry. It will start with a set of preparatory lectures on fundamental concepts necessary to understand the more advanced material that will follow. Evaluation will be based on two comprehensive exams and the presentation of a paper from current literature by each student. The papers will use methods that have been taught during the course to study a biological problem. The class will meet two times a week.
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Mathematics: Population models, differential equations, and eigenvalues[2010 Jan Term]
Instructor: E Lebow
Credits: 3 (Basic or Advanced)
Duration: Feb 19, 2010 May 4, 2010
Schedule: TF 2:00PM 3:30PM, LH3
Outline: Difference equations, exponential growth. Some nonlinear equations, and what they model. Systems of difference equations, and what they model. Review of matrix algebra, determinants, etc. Eigenvalues and eigenvectors. Using eigenvalues and eigenvectors to solve systems of difference equations. Dominant eigenvalues, stability. Introduction to programming (in Scilab) for use in simulating population models.Equilibria and linearising nonlinear difference equations. Complex eigenvalues. Review of derivatives. Differential equations, and analysing them--eigenvalues, eigenvectors, stability, equilibria, linearising, and drawing vector fields.




