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Introduction to Laboratory Practices [2009 Aug Term]

Instructors: SP Koushka, D Nair, U Ramakrishnan

Credits: 0 (Required)
Duration: Aug 4, 2009 – Aug 19, 2009
Schedule: TWRF 4:00PM – 6:00PM, Teaching Lab

Outline: Introduction to basic laboratory practices and techniques. Lab safety and etiquette. Maintaining lab notebooks.

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Physical Biochemistry [2009 Aug Term]
Instructors: MK Mathew, JB Udgaonkar

Credits: 3 (Basic)
Duration: Aug 24, 2009 – Dec 15, 2009
Schedule: MWF 9:00AM – 10:30AM, LH2

Outline: Structural organization of proteins, nucleic acids and membranes. Thermodynamics: the laws; biochemical thermodynamics; statistical thermodynamics; stabilizing interactions in biomolecules; thermodynamics of ion, electron and solute transport; association between molecules. Macromolecular dynamics: fluorescence methods; hydrogen exchange; biomolecular motors; kinetics; enzyme catalysis; mass spectrometry of biomolecules.        

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Molecular Biology [2009 Aug Term]
Instructor: DT Nair

Credits: 3 (Basic)
Duration: Sep 1, 2009 – Nov 26, 2009
Schedule: TR 9:15AM – 10:15AM

Outline: Nucleic acid structure. The genetic code. Prokaryotic transcription and translation. DNA replication and recombination; mutations and repair. Eukaryotic transcription. Bioinformatics. RNAi/microRNA.

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Developmental Biology [2009 Aug Term]
Instructors: K VijayRaghavan, M Inamdar (JNCASR)

Credits: 3 (Basic)
Duration: Aug 26, 2009 –
Schedule: WF 2:00PM – 4:00PM

Outline: The course will aim to understand cell- fate specification and morphogenesis in animal and plant development from a mechanistic perspective. The latter means that there will be a attempt to develop a molecular- and cellular-understanding as opposed to a descriptive one.

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Mathematics: Pre-calculus and differential calculus [2009 Aug Term]

Instructor: M Thattai

Credits: 3 (Basic)
Duration: Aug 25, 2009 – Oct 29, 2009
Schedule: TR 2:00PM – 3:30PM, LH3
Outline: Pre-calculus and differential calculus. Graphs and functions. Linear functions, power functions, polynomials, exponentials, logarithms. Graphical methods: scaling, inverse functions. Limits, derivatives. Maxima and minima; inflections. Basic calculus rules: product rule; chain rule. The integral. Differential equations.

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Mathematics: Linear Algebra: Vectors and Matrices [2009 Aug Term]

Instructor: E Lebow

Credits: 3 (Basic)
Duration: Aug 24, 2009 – Oct 28, 2009
Schedule: MW 2:00PM – 3:30PM, LH3; Tutorial: T 10:30AM – 11:30AM
Outline: Systems of linear equations and Gaussian elimination. Vector spaces. Inner product. Determinants. Eigenvalues and eigenvectors.

 

Concepts in Chemical Biology [2009 Aug Term]
Instructor: Y Krishnan

Credits: 3 (Basic)
Duration: Sep 1, 2009 – Oct 29, 2009
Schedule: TR, 10:30AM – 12:30PM, FFSH

Outline: Chemical biology of macromolecules. DNA and RNA structure. Control of gene expression. DNA replication. DNA damage and repair. RNA processing. Ribosomes and translation. RNA control of gene expression. Chemical sensors. Chemical genetics.

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Scientific Writing [2010 Jan Term]
Instructor: G Hyde

Credits: 0 (Required)
Duration:
Schedule:

Outline: An eight week course that aims to upgrade your scientific writing skills. Clear and logical prose. Text composition. Argument maps. Extracting arguments from a text.

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Molecular Genetics [2010 Jan Term]
Instructor: Prof. Usha VijayRaghavan, Dr. K. Muniappa, Dr. Utpalnath, Dr. Sandhya P. Koushika

Credits: 3 (Basic)
Duration: Jan 12, 2010 – April 17, 2010
Schedule: TR 12:00 – 1:00PM
Venue : IISc Biochemistry Jubilee Hall

Outline: The logic and techniques of genetic analysis; epistasis, suppressors, genetic interaction networks and reverse genetics and genomics. Illustration of the application of genetic analysis of specific pathways in model organisms  of C. elegans, Drosophila, Yeast, bacteriophage and plants. Examples discussed include genetics of phage morphogenesis, bacterial chemotaxis, regulation of cell cycle, genome rearrangements, genetic recombination, transposition, signaling and developmental mechanisms, synapse formation and function.

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Cell Biology [2010 Jan Term]
Instructors: S Mayor and others

Credits: 2 (Advanced)
Duration:
Schedule:

Outline: Cellular organization. Intracellular traffic. Motors and the cytoskeleton. Cell signalling. Chromatin structure. Organellar biogenesis. Cell cycle. Apoptosis.

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Molecular Motors, Tracks and Transport [2010 Jan Term]
Instructors: G Menon (IMSc Chennai), S Koushika and others

Credits: 2 (Advanced)
Duration: Jan 23, 2010 – Jan 28, 2010
Schedule: Meeting in Pondicherry

Outline: We discuss the following areas: molecular motors, the cytoskeleton, mitosis, principles of intracellular transport, biophysics of molecular motors, and modeling of intracellular transport. See workshop website for more information. Students interested in taking this as a course for credit please speak to Sandhya before December 15th, 2009.

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Basic Neuroscience [2010 Jan Term]
Instructors: US Bhalla, S Chattarji, S Sane

Credits: 3 (Basic)
Duration: Feb 1, 2010 – Apr 31, 2010
Schedule: M 9:30AM – 11:00AM, LH3; WF 11:30AM – 1:00PM, LH3

Outline: Philosophy of neuroscience. Neuronal physiology: Cable theory, voltage and ligand-gated channels, Ionic potentials and ionic currents. Computation with neurons: Dendritic and synaptic integration, voltage-gated channels and nonlinearities, integrate and fire neurons, neural coding. Synaptic signaling: biochemical basics, computing with chemicals, amplification, summation, temporal computation, bistability. Neuroanatomy: Brain regions and functions. Synaptic function and synaptic plasticity. Invertebrate neurons and networks. Medical implications.

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Evolutionary Biology [2010 Jan Term]
Instructors: U Ramakrishnan, S Quader

Credits: 3 (Basic)
Duration: JAN 1, 2010 - Mid April 2010
Schedule: M 11:30AM -  1:00PM, LH2; WF 2:00PM - 3:30PM LH3;
Outline: Biological diversity Evidence for evolution through the fossil record. Macroevolution. Evolution above the species level. Adaptation and the adaptationist approach to studying behaviour ecology and life-history. Evolution and variation across space. Micro evolutionary processes. The theory of natural selection. Evolution of phenotypic variation and the relevance of evolution and its study in human society. Species co-evolution, evolution and development. Genome evolution.

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Clinical Biology [2010 Jan Term]
Instructor: S Krishna

Credits: 2 (Advanced)
Duration:
Schedule:

Outline: Leukemia as a system to familiarize basic scientists with research issues in the context of disease biology, covering the study of  genetics and molecular biology, cytogenetics, hematological lineage analysis, drug discovery and related structural biology.

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Biomolecular Spectroscopy and Bioanalytical Chemistry [2010 Jan Term]
Instructors: M Puranik, D Schwudke

Credits: 3 (Basic)
Duration: Feb 1, 2010 –
Schedule:

Outline: The course will cover theoretical aspects and applications of modern techniques in spectroscopy and bioanalytical chemistry. It will start with a set of preparatory lectures on fundamental concepts necessary to understand the more advanced material that will follow. Evaluation will be based on two comprehensive exams and the presentation of a paper from current literature by each student. The papers will use methods that have been taught during the course to study a biological problem. The class will meet two times a week.

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Mathematics: Population models, differential equations, and eigenvalues[2010 Jan Term]

Instructor: E Lebow

Credits: 3 (Basic or Advanced)
Duration: Feb 19, 2010  May 4, 2010
Schedule: TF 2:00PM  3:30PM, LH3

Outline: Difference equations, exponential growth. Some nonlinear equations, and what they model. Systems of difference equations, and what they model. Review of matrix algebra, determinants, etc. Eigenvalues and eigenvectors. Using eigenvalues and eigenvectors to solve systems of difference equations. Dominant eigenvalues, stability. Introduction to programming (in Scilab) for use in simulating population models.Equilibria and linearising nonlinear difference equations. Complex eigenvalues. Review of derivatives. Differential equations, and analysing them--eigenvalues, eigenvectors, stability, equilibria, linearising, and drawing vector fields.


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