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Animal Strain Info

NCBS Stock ID Strain ID Full ScientificStrain Name Repository Status Stock Status species Strain Type Lab of Origin Original Stock ID Genetic background Breeding Scheme (f)x(m) Eye/Coat colour Information on Strain Specifics Genotype of Litters Required Date of Import to AF Number of (f) and (m) Imported MTA ID Notes Repo
Notch1 Flox/Flox Notch1 Flox/Flox Public Live Mus Musculus Tg, Targeted KO Freddy Radtke EPFL B6 homo X homo Black Coat color Freddy Radtke EPFL RL lab Public
Ai9/Ai9; Lhx2cKO/ Lhx2cKO Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Ncbs ; Lhx2tm1Monu/Ncbs Public Live, Cryo-S Mus Musculus coumpound, cKO Shubha Tole (TIFR Mumbai) Cryo + JAX compound from JAX#007909 + MGI:3772179 mixed - original Cryo males were agouti Tuesday, November 22, 2016 Shubha Tole (TIFRmumbai) for Cryo Stocks, JAX, BM BM - imported new set of animals for rederivation and cryo from TIFRmumbai 6 March 2021. Public
Axin2-d2EGFP Tg(Axin2-d2EGFP)5Cos/Ncbs Public Live, Cryo-S Mus Musculus Transgenic-Reporter, Random Insertion Frank Costantini, Columbia University- (NCBS Rederived from Shubha Tole-Mumbai TIFR, Aug2016) MGI:3836891 mixed 13 pups per litter at TIFR-Mumbai; NCBS=? Friday, August 12, 2016 Rederived via embryo Transfer from Shubha Tole-TIFR Mumbai- Stocks - From Frank Costantini, Columbia University, Shubha Tole (TIFRmumbai) for cryo stock MTA: Frank Costantini, Columbia University & Ramkumar Sambasivan direct Agreement- Public
B6 albino B6(Cg)-Tyrc-2J/J Public Live Mus Musculus transgenic-Spontaneous Mutation Jax JAX:000058 Albino- C57Bl6 mutated @ tyrosinase (Tyr gene) Homo X Homo albino coat, red eyes B6 albino mice are used to generate blastocysts that can be used for microinjection of genetically modified C57BL/6J embryonic stem cells. Following implantation and gestation, resulting offspring that are chimeric for the donor embryonic stem cells and t yes- express Tyr<c-2J> Saturday, December 23, 2023 2females and 2 males Public
B6/J_2019 C57BL/6JNcbs [2019] Public Live, Cryo-S Mus Musculus JAX JAX#000664 Friday, September 13, 2019 2 breeding pairs JAX to TIFRHyd Public
B6D2 F1 B6JD2F1/JNcbs Public Live, Cryo-E Mus Musculus WT F1 hybrid NCBS AF / ACRC components of JAX# 000664 and JAX# 000671 (f)C57Bl/6J X (m)DBA2/J black N ACRC JAX: Useful as a genetic background for transgenic/knockout creation, as well as other deleterious mutations. Research applications include radiation and behavioral research, and safety and efficacy testing, bioassays of nutrients, drugs, pathogens, and hormones. [old stock ID = acrc:00003] Public
B6J albino B6(Cg)-Tyrc-2J/JNcbs Public Live, Cryo-E, Cryo-S Mus Musculus JAX JAX#000058 B6J Homozygote X Homozygote albino / white Friday, September 13, 2019 3 breeding pairs JAX B6(Cg)-Tyrc-2J/J, or B6-albino mice, are C57BL/6J mice that carry a mutation in the tyrosinase gene. Pigment is completely absent from skin, hair and eyes in mice homozygous for Tyrc-2J. This unique characteristic makes these mice ideal for creation of novel strains with targeted mutations (gene knockouts) on the B6J background. Public
B6N/J_2022 C57BL/6NJNcbs Public Live Mus Musculus Inbred Strain JAX -> NCBS JAX#005304 Inbreeding Black Coat color Friday, November 25, 2022 4F and 4M JAX Arrived on 24 Nov 2022. These are from the standard barrier JAX facility and are planned to rederive to SOPF status. Public
B6N22 D2/21 F1 B6N22 D2/21 F1 Public Live, Cryo-S Mus Musculus wild type hybrid MGEF B6N/J *DBA/2 B6N/J *DBA/2 Public
B6NJ_2020 C57BL/6NJNcbs [2020] Public Live, Cryo-E, Cryo-S Mus Musculus inbred JAX JAX#005304 B6N inbred black no but genetic monitoring recommended Friday, November 27, 2020 6 breeding pairs JAX Public
BALB/cA_25 BALB/cJ Public Live Mus Musculus Inbred ATNT Strain #:000651 albino Sibling x Sibling white coat colour Friday, April 4, 2025 Balb C procured from ATNT lab Hyderabad on 4th April 2025 Public
betaCat-Flox B6.129-Ctnnb1tm2Kem/Ncbs (beta-Catenin cKO) Public Live, Cryo-S Mus Musculus Knockin, conditional knock-out Rolf Kemler, MPI-IE Freiburg (NCBS imported via Shubha Tole-TIFR Mumbai) MGI:2148567 also available as JAX: 004152 mixed 13 pups per litter at TIFR-Mumbai; NCBS=? Friday, August 12, 2016 Rederived via embryo Transfer from Shubha Tole-TIFR Mumbai- Stocks Rolf Kemler, MPI-IE Freiburg and Ramkumar Sambasivan direct agreement, Shubha Tole (TIFRmumbai) for cryo stock MTA: Rolf Kemler, MPI-IE Freiburg and Ramkumar Sambasivan direct agreement- ST-CryoStocks. [old stock ID=acrc:00007] Public
betaCat-loxEx3 Ctnn1b tm1Mmt (beta-Catenin GOF) Public Live, Cryo-S Mus Musculus Knockin, conditional Gain of function Makoto Mark Taketo, Kyoto University (NCBS imported via Shubha Tole-TIFR Mumbai) MGI:1858008 mixed 16 pups/litter at TIFR Mumbai - NCBS=? Friday, August 12, 2016 Rederived via embryo Transfer from Shubha Tole-TIFR Mumbai- Stocks Makoto Mark Taketo, Kyoto University, Shubha Tole (TIFRmumbai) for cryo stock MTA: Makoto Mark Taketo, Kyoto University and Ramkumar Sambasivan direct agreement- Public
C3HFe_2021 C3HeB/FeJNcbs [2021] Public Live, Cryo-E Mus Musculus JAX JAX#000658 Thursday, June 24, 2021 2 breeding pairs JAX This general purpose strain shares a common origin with C3H/HeJ and C3H/HeOuJ. Unlike C3H/HeJ, it carries a normal allele at the Tlr4 locus, but is homozygous for Pde6brd1, which causes retinal degeneration. C3HeB/FeJ inbred mice have been found to be extremely susceptible to virulent Mycobacterium tuberculosis. They develop pulmonary tuberculosis and die within 25-28 days of infection with 105 CFU of Erdman strain of M. tuberculosis (Kramnik et al, 1998). Several QTL have been identified that contribute to the M. tuberculosis susceptibility (Sissons et al., 2009) Public
CamK2 B6.Cg-Tg(Camk2a-cre)T29-1Stl/JNcbs Public Live, Cryo-S Mus Musculus Congenic, Transgenic JAX -> JNcbs JAX# 005359 inbred (sibling X sibling) (f)CamK2 X (m)CamK2 black litter size 5-10 pups N 2 duos Global JAX/NCBS/Instem transfer agreements_2017, USB New stocks arrived on 9th August 2022. Public
CamK2-Cre, E2-2f/f B6.Cg-Tg(Camk2a-cre)T29-1Stl/J, E2-2f/f Public Live Mus Musculus multigenic/compound JAX and Dan Holmberg (Sweden) components of JAX# 005359 and MGI:3798811 mixed Public
CaMK2a-CreERT2 [NY], E2-2f/f, Thy1-GFP lineM;R26-Stop-fl-Ai9-tdTomato B6;129S6-Tg(Camk2a-cre/ERT2)1Aibs/JNcbs [NY], Tcf4tm1.1Hmb (E2-2-)/Ncbs, STOCK Tg(Thy1-EGFP)MJrs/JNcbs [Thy1-GFP line M];B6.Cg-Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/JNcbs [Ai9(RCL-tdT)] Public Live, Cryo-S Mus Musculus compound JAX and Dan Holmberg (Sweden) components of JAX# 012362 and MGI:3798811 and JAX#007788 mixed Global JAX/NCBS/Instem transfer agreements_2017, Dan Holmberg (Sweden) The Thy1-EGFP allele was recovered from IISC stocks- most likely: STOCK Tg(Thy1-EGFP)MJrs/J [Thy1-GFP line M]-- The CaMK2a-CreERT2 allele was imported from two separate sources (NY and Dresden-MPI). This stock carries the NY CaMK2a-CreERT2 allele. Public
CBA_2021 CBA/JNcbs [2021] Public Live, Cryo-E, Cryo-S Mus Musculus JAX JAX#000656 Thursday, June 24, 2021 2 breeding pairs JAX Public
CD1-2019 Crl: CD1 (IGS) Elite Public Live, Cryo-E, Cryo-S Mus Musculus Charles River USA Crl:022 - Elite SPF mini Outbred albino Thursday, May 30, 2019 5 breeding pairs from Crl USA via Hyalasco Crl USA Public
CMVCre B6.C-Tg(CMV-cre)1Cgn/JNcbs Public Live, Cryo-S Mus Musculus Congenic, Transgenic (Recombinase-expressing) JAX JAX# 006054 Homozygote x Hemizygote (Transgene appears to be X-linked) black Y 4 males + 4 females (26-Feb-2009) Global JAX/NCBS/Instem transfer agreements_2017 Stock Cryopreserved for Maneesha Inamdar (JNCSAR). - JAX: The transgene appears to be X-linked since transgene transmission through males is restricted to female offspring. Public
Csf1r Flox B6.Cg-Csf1rtm1.2Jwp Public Live, Cryo-S Mus Musculus Imported from IISC - originally a JAX stock JAX#021212 B6 Wednesday, November 18, 2020 JAX relocation MTA 3 males imported from IISC [Narendrakumar Ramanan] - rederived at MGEF- for SR lab. Public
Cx40CreER, tdTAi9 [Mixed]; Cdk1-L Cx40CreER, B6.Cg-Gt(ROSA)26Sortm9(CAG-tdTomato)Hze [Ai9]; 129S(B6N)-Cdk1tm1Eddy/JNcbs Public Live Mus Musculus Compound Cx40CreER, tdTAi9 [Mixed]- Red-Horse Lab - Stanford University and Ai9 allele originally from JAX#007909 , Cdk1-L- JAX Cx40CreER, tdTAi9 [Mixed] -Red-Horse Lab - Stanford University and Ai9 allele originally from JAX#007909, Cdk1-L - JAX # 028028 Public
Cx40CreER, tdTAi9 [Mixed]; Gpr177Fx Cx40CreER, B6.Cg-Gt(ROSA)26Sortm9(CAG-tdTomato)Hze [Ai9]; Wlstm1.1Whsu/JNcbs [Gpr177Fx] Public Live Mus Musculus Compound Red-Horse Lab - Stanford University and JAX Ai9 allele originally from JAX#007909, Gpr177Fx- JAX#027484 Red-Horse Lab - Stanford University, JAX Public
db/+_2018 BKS.CgDock7< m> +/+ Lepr<db>/J Ncbs Public Live, Cryo-E, Cryo-S Mus Musculus Diabetic model - double mutant - spontaneous mutations JAX JAX#000642 BKS Het X Het (db phenotype is background specific) Leprdb= black, fat; Related Genotype: a/a + Leprdb/+ Leprdb ; Dock7m Leprdb= black, lean; Related Genotype: a/a Dock7m +/+ Leprdb; Dock7m= misty (grey), lean; Related Genotype: a/a Dock7m +/Dock7m + Wednesday, February 21, 2018 1 breeding pair - Male died before breeding! + 2 new breeding pairs in Feb2018 Global JAX/NCBS/Instem transfer agreements_2017 September 2017: 1 breeding pair was imported and quarantined. when setting up mating after quarantine- a small protrusion was observed in the sternum region- the Male died with severe Ascites phenotype a few days later- Female is fine. 2 New Breeding pairs (2M+2F) imported in Feb2018. Public
DBA2_2021 DBA/2JNcbs [2021] Public Live, Cryo-E, Cryo-S Mus Musculus JAX JAX# 000671 Thursday, June 24, 2021 4 breeding pairs JAX Public
Emx2-Cre Emx2-Cre/+ [RIKEN] Public Live, Cryo-S Mus Musculus RIKEN-CDB CDB0020K B6/N ×(-/+) Thursday, November 22, 2018 1 vial of 2 cell embryos RIKEN-CDB sperm QC efficiency:38.7% Control sperm efficiency for current QC session:98.03% Public
FGFR1delta FGFR1delta FRS Public Live, Cryo-S Mus Musculus RIKEN-CDB + From Soriano Lab B6/N B6/N WT X (+/-) Monday, January 29, 2018 1 CryoVial (= 57 2-cell embryos) Phil Soriano Public
GCaMP 5.17 C57BL/6J-Tg(Thy1-GCaMP6f)GP5.17Dkim/JNcbs Public Live Mus Musculus Transgenic (Inserted expressed sequence) JAX JAX# 025393 Hemizygote x Noncarrier black 5-10 pups per litter N 3 trios Global JAX/NCBS/Instem transfer agreements_2017 USB Public
GCaMP 5.17_2018 C57BL/6JTg(Thy1GCaMP6f)GP5.17Dkim/J Public Live, Cryo-S Mus Musculus Transgenic (Inserted expressed sequence) JAX JAX# 25393 Hemizygote x Noncarrier OR Noncarrier x Hemizygote Black Wednesday, February 21, 2018 2 (Noncarrier X Hemi) breeding pairs Global JAX/NCBS/Instem transfer agreements_2017 USB Public
gdTCR KO gdTCR^-/- Public Live, Cryo-S Mus Musculus isogenic Havran (TSRI) Homozygote x Homozygote Black/Black no Havran (TSRI) CJ Public
Htr2a B6;129SB6F1-Htr2a^tm1MMP/ncbs Public Live, Cryo-E, Cryo-S Mus Musculus Targeted Knockout (Exon1 + part of intron2 deletion) MMP B6; 129 Homozygous & Heterozygous Breeding Agouti/ Black 6-9 pups per litter KOF_GTG GAG AGG CTA TTC GGC TAT GA; KOR_TGC CTC GTC CTG CAG TTC ATT C; WTF_GGT ACC GGT GGC CTT TGC C; WTR_tac gga tat ggt cca cac cgc aat NCBS ACRC MMP_______________ original donor ESstrain: G4 ES cells- First Exon + part of Secon intron were deleted. KO PCR band- 200bp; WT PCR band- 201bp Public
Ift88-fl B6.129P2-Ift88tm1Bky/JNcbs Public Live, Cryo-S Mus Musculus Targeted (Conditional ready (e.g. floxed), No functional change) JAX ->NCBS JAX# 022409 homozygotes can be bred together black Thursday, September 20, 2018 1 breeding pair (Homozygoytes) Global JAX/NCBS/Instem transfer agreements_2017 Sperm QC efficiency-75.8% Public
Jag1-flox B6;129S-Jag1tm2Grid/JNcbs Public Live, Cryo-S Mus Musculus Targeted Mutation JAX -> ACRC JAX#010618 mixed Wednesday, November 27, 2019 JAX These floxed mutant mice possess loxP sites flanking exon 4, which encodes the DSL (Delta-Serrate-Lag2) domain, of the Jag1 gene. This strain may be useful for generating conditional mutations for studies of Notch signaling during development. Public
K14Cre (B6) Tg(KRT14-cre)1Efu/Ncbs (C57BL6) Public Live Mus Musculus Transgenic Elaine Fuchs at Rockefeller University Homozygous breeding black 10-12 pups per litter NO Elaine Fuchs at Rockefeller University, Colin Jamora CJ Public
K14Snail (CD1) K14 Snail Tg (CD1 background) Public Live, Cryo-S Mus Musculus Elaine Fuchs (Rockefeller University) albinos Yes Elaine Fuchs (Rockefeller University), Colin Jamora for Cryo CJ; mice died during shipment; repeated import Public
K14Snail(B6) K14 Snail Tg (C57Bl6 background) Public Live, Cryo-S Mus Musculus congenic Elaine Fuchs (Rockefeller University) inbred (sibling X sibling) black 6-8 pups per litter Yes CJ Public
KPCBA KrasG12D; Trp53R270H; Pdx1-Cre ; Brca2-Tr1491; Brca2-F11; Aldh2tm1a/tm1a Public Live, Cryo-S Mus Musculus compound MRC? Mixed (C57/BL6J; FVB/N; 129Sv) Friday, June 1, 2018 4 breeding pairs Ashok V, MRC compound breeding of 6 different alleles: 1) Lox-STOP-Lox-KrasG12D. 2) Lox-STOP-Lox-Trp53R270H. 3) Pdx1-Cre. 4) BrCa2-Tr1491. 5) BrCa2-F11. 6) Aldh2tm1a/tm1a. - Brca2-Tr allele is embryonic lethal in the homozygous state (not when heterozygous); Only particular combinations of alleles will lead to the appearance of pancreatic tumours, which eventually result in death of the animals. Public
LE-Crl LONGEVANS - (Charles River) Public Live Rattus norvegicus WT Crl LEH WT X WT Public
Leh/Arid1b Leh/Arid1b Public Live Rattus norvegicus medical college of Wisconsin LEH Friday, November 15, 2019 Public
Leh/Dyrk Leh/Dyrk Public Live Rattus norvegicus medical college of Wisconsin LEH Friday, November 15, 2019 Public
Leh/Grin2b Leh/Grin2b Public Live Rattus norvegicus medical college of Wisconsin LEH Friday, November 15, 2019 Public
Lewis LEW/Crl - LEWIS RAT Public Live Rattus norvegicus INBRED RAT Charles River UK via Hylasco LEW/Crl - strain Code: 004 White (albino) Friday, July 31, 2020 3 breeding pairs CRL - Hylasco PV lab Public
Lgr5-EGFP-IRES-creERT2 B6.129P2-Lgr5tm1(cre/ERT2)Cle/JNcbs Public Live, Cryo-S Mus Musculus Targeted (Recombinase-expressing, Reporter, Inducible) JAX JAX#008875 +/+ sibling x Heterozygote homozygous lethal Friday, September 13, 2019 2 breeding pairs JAX Public
Lsd1cKO B6.129-Kdm1atm1.1Sho/JNcbs Public Live Mus Musculus Congenic, Targeted Mutation JAX -> NCBS JAX#023969 When maintaining a live colony, homozygous mice may be bred together. Black Coat color These LSD1fl/fl mutant mice may be useful for studying the epigenetic mechanisms required for proper hematopoietic maturation, as well as the role of LSD1 in activity-evoked transcription of immediate early genes (IEGs) that impact memory formation, emoti Thursday, April 14, 2022 6 males and 5 Females JAX Public
MindinKO(B6) Mindin KO (C57Bl6) Public Live, Cryo-S Mus Musculus He Lab (Duke University) KO X KO Black 6-8 pups per litter No He Lab (Duke University), Colin Jamora CJ Public
Ngn1-457Cre STOCK Tg(Neurog1-cre)1Jejo/JNcbs Public Live Mus Musculus transgenic Cre JAX -> ACRC JAX#012859 mixed - (C57BL/6J & SJL/J) Wednesday, November 27, 2019 JAX Public
NSG_2020 NOD.Cg-Prkdc<scid> Il2rg<tm1Wjl>/SzJNcbs Public Live, Cryo-E, Cryo-S Mus Musculus immunocompromised / double mutant JAX JAX#005557 NOD albino Females are Homozygotes for Prkdc<scid> and Il2rg<tm1Wjl>- Males are Homozygotes for Prkdc<scid> and hemizygotes for Il2rg<tm1Wjl> Friday, November 27, 2020 5 breeding pairs JAX NSG mice require Lab PI specific JAX MTAs, _active NSG MTAs for: CJ + JD + MI + SR + SRD + HSG + SK Public
PARP1-KO 129S-Parp1tm1Zqw [ADPRT] Public Live, Cryo-S Mus Musculus ko JAX-> IISc-> NCBS JAX#002779 JAX, IISc - N. Ravi Sundaresan <rsundaresan@iisc.ac.in> mice maintained in V1 for DP lab / IISC Ravi Sundaresan collaborative work. Public
Pcdh15-n38YF-HA Pcdh15 Swap Mt ex 38#28(KI/+) F1 EMZY; Tg(Pgk1-cre)1Lni/Ncbs Public Live Mus Musculus Compound Pcdh15 Mt EX38-flag- RIKEN, CDBO186E; PGK cre- Pasteur Institute Paris (Yvan Lallemand), MGI:2178050 ; also available as JAX#020811 (on B6) Pcdh15 Mt EX38-flag- RIKEN, CDBO186E; PGK cre- Pasteur Institute Paris (Yvan Lallemand), MGI:2178050 ; also available as JAX#020811 (on B6) RIKEN-CDB and Pasteur Institute Paris (Yvan Lallemand) Pcdh15-n38YF-HA - cross of Pcdh15 mt ex38-flag with pgk-cre. It will change all the tyrosine residues to phelyalanine on exon 38 of pcdh15 and than tagged with HA tag, which will be different than normal Pcdh15 mt ex38-flag. Public
Pcp2Cre B6.129-Tg(Pcp2-cre)2Mpin/JNcbs Public Live, Cryo-S Mus Musculus Transgenic (Recombinase-expressing) JAX JAX# 004146 B6.129 Homozygote x Homozygote black 6 to 9 litter size. Gender varies with each litter.Canabilization was observed in two cages twice Yes 3 breeding pairs JAX - NCBS relocation agreements Public
PepBoy_2019 B6.SJL-Ptprca Pepcb/BoyJNcbs Public Live, Cryo-E, Cryo-S Mus Musculus JAX JAX#002014 C57BL/6J sibing X sibling black Friday, September 13, 2019 2 breeding pairs JAX to TIFRHyd, JAX instem/ncbs agreements TIFRHyd- This C57BL/6 congenic strain is used widely in transplant studies because it carries the differential pan leukocyte marker Ptprca, commonly known as CD45.1 or Ly5.1. Wild-type C57BL and BALB/c inbred strains express the Ptprcb (CD45.2 or Ly5.2) allele.- A spontaneous mutation in the Ncr1 gene is segregating in this strain- Public
PGKCre Tg(Pgk1-cre)1Lni/Ncbs Public Live, Cryo-S Mus Musculus Transgenic (Recombinase) Pasteur Institute Paris (Yvan Lallemand) MGI:2178050 ; also available as JAX#020811 (on B6) mixed (strain of origin: (BALB/c x C57BL/6)F2) Homozygous breeding Coco or Black 8-12 pups per litter N Pasteur Institute Paris (Yvan Lallemand), JAX RS Public
R26-DTAlky B6.129P2-Gt(ROSA)26Sortm1(DTA)Lky/JNcbs -[R26-DTAlky] Public Live Mus Musculus Targeted (Conditional ready (e.g. floxed), Inserted expressed sequence, No functional change) JAX ->NCBS JAX# 009669 B6 Homozygote x Homozygote black Thursday, September 20, 2018 1 breeding pair (Homozygoytes) JAX Public
R26R-H2B-EGFP R26R-H2B-EGFP [H2BG#42(loxp/loxp)] Public Live, Cryo-E, Cryo-S Mus Musculus targeted reporter [nucleus] RIKEN-CDB CDB0203K B6/N Monday, January 29, 2018 2 cryo-vials RIKEN-CDB R26R reporter lines generated by inserting a series of cDNAs for fluorescent fusion proteins into the ROSA26 locus. the R26R alleles are the <conditional> loxP-PGKNeo pA-loxP alleles. (http://www.clst.riken.jp/arg/reporter_mice.html). Public
R26R-mito-DarT [#12] B6N;DBA2-Rosa26^em2(LSL-DarT-FLAG-IRESeGFP)Mgef/Ncbs [from founder#12] Public Live, Cryo-S Mus Musculus crispr/Cas9 targeted knockIn MGEF MGEF / BLiSC, Raj Ladher RajLadher Lab. MGEF project: Inj21_RL_Mona_R26-DarT-KI_609 Public
RBPj flox B6.129S2-Rbpj<tm1Kyo>/HonRbrcNcbs Public Live Mus Musculus Targeted Mutation Congenic RIKEN- CDB- Mitsuru Morimoto RBRC01101 - PMID:17681139 originaly on C57BL/6NCrSlc ? but litters have Black and Albino pups!! (Heterozygote x C57BL/6N) - or Het X Het - Only Black animals should be used for mating Mitsuru confirms that litters are black pups with occasional albino pups- Homos are embryonic lethal - die by E10.5 YES Thursday, November 22, 2018 1 vial of 2 cell vitrified embryos- Vitrified RIKEN on 2017.6.30 & MGEF cryorecovered Black and Albi pups on 28 May 2019 Mitsuru Morimoto - RIKEN-CDB Developed by Dr. Honjo, Faculty of Medicine, Kyoto University in 1995. RBP-J, recombining binding protein suppressor of hairless (Drosophila) which is a transcriptional factor of a Notch/RBP-J signaling pathway play a role in fate determination in various lineages. RBP-J homozygous mutant mice show severe growth retardation at 8.5 days of gestation, incomplete turning of the body axis, microencephaly, abnormal placental development, anterior neuropore opening and defective somitogenesis at 9.5 days of gestation, and die before 10.5 days of gestation. Public
RCE Gt(ROSA)26Sortm1.2(CAG-EGFP)Fsh/Ncbs [RCE:FRT] Public Live, Cryo-S Mus Musculus Targeted Gordon Fishell (NY) MGI:4420764 ; MMRRC Stock No: 32038-JAX JAX, Gord Fishell, Harvard Medical School HSG Public
Rud lox Rudhira lox / Ncbs (= Bcas3 lox ; breast carcinoma amplified sequence 3) Public Live, Cryo-S Mus Musculus RIKEN -> Ncbs original: C57BL/6 × CBA (transgenic) Homozygote X Homozygote black Stock Cryopreserved for Maneesha Inamdar (JNCSAR). Public
Scgb1a1-CreER, tdT B6N.129S6(Cg)-Scgb1a1tm1(cre/ERT)Blh/J, B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/J /[Ncbs] Public Live Mus Musculus compound, double targeted JAX compound of JAX#016225 and JAX#007914 Scgb1a1-CreER^Cre/Cre X tdTomatoAi14^tdT/tdT JAX - NCBS relocation agreements AG Public
SD-21 Sprague Dawley (SD) [Feb 2021 Hylasco stocks] Public Live Rattus norvegicus Hylasco Hyderabad - Charles River Crl:CD (SD) IGS (Crl#001) Friday, February 26, 2021 10 Males + 10 Females Public
Six1-Cre; RBPj flox B6N Six1-Cre/+ (B6N) [mSix1-21-NLSCre]; B6.129S2-Rbpj<tm1Kyo>/HonRbrcNcbs Public Live Mus Musculus Compound RIKEN-CDB to ACRC RBPj flox-RBRC01101 - PMID:17681139, RIKEN-CDB, RBPj flox from Mitsuru Morimoto Public
Six1-Cre;Jag1-flox B6N Six1-Cre/+ (B6N) [mSix1-21-NLSCre]; B6;129S-Jag1tm2Grid/JNcbs Public Live Mus Musculus Compound Six1-Cre- RIKEN-CDB + from Dr Shigeru Sato in Jichi Med Univ; Jag1-flox- JAX Six1-Cre- RIKEN-CDB + from Dr Shigeru Sato in Jichi Med Univ; Jag1-flox =JAX#010618 RIKEN-CDB, JAX Public
Sox10-Cre B6;CBA-Tg(Sox10-cre)1Wdr/JNcbs Public Live, Cryo-S Mus Musculus Transgenic (Recombinase-expressing) JAX ->NCBS JAX# 025807 B6;CBA Noncarrier x Hemizygote OR Hemizygote x Noncarrier black Thursday, September 20, 2018 1 breeding pair (Hemizygoytes) JAX The Jackson Laboratory live colony in 2017 exhibits white belly spots (not linked to presence of the transgene). Public
Sox2 loxP STOCK Sox2tm1.1Lan/JNcbs Public Live Mus Musculus Targeted (Conditional ready (e.g. floxed), No functional change) JAX JAX#013093 mixed Homozygote MALES x HET females is recommended ; HOMO X HOMO are very poor breeders YES Friday, November 27, 2020 3 Males JAX From Jax: "When maintaining a live colony, homozygous mice may be bred together. It is the experience of colonists at The Jackson Laboratory that homozygous breeding pairs produce few offspring, as does breeding heterozygous females with homozygous males. Therefore, we also maintain this strain by breeding homozygous females with heterozygous males. Public
Sox2 loxP; Emx2-Cre Sox2tm1.1Lan/JNcbs ; Emx2-Cre [Riken] Public Live Mus Musculus JAX -> NCBS & RIKEN-CDB compound of JAX#013093 & CDB0020K mixed JAX, Riken-CDB (Kobe) Public
Sox2 loxP; Lgr5-EGFP STOCK Sox2tm1.1Lan/JNcbs; B6.129P2-Lgr5tm1(cre/ERT2)Cle/JNcbs Public Live Mus Musculus JAX compound of JAX#013093 & JAX#008875 JAX Public
Sst-IRES-Cre B6N.CgSst<tm2.1(cre)Zjh>/J Public Live, Cryo-S Mus Musculus Targeted (Recombinase-expressing) JAX JAX# 18973 B6N Heterozygote x Wild-type OR Wild-type x Heterozygote or HET X HET Black Wednesday, February 21, 2018 2 (HET X WT) breeding pairs JAX @JAX- Mice were bred to C57BL/6NJ inbred mice (Stock No. 005304) for many generations using a marker-assisted, speed congenic approach to generate this C57BL/6NJ-congenic strain. When maintaining the live congenic colony, homozygous mice may be bred together. Researchers may consider using heterozygous Sst-IRES-Cre mice in behavioral studies; please see strain description for more details. USB Public
TBra B6 x B6Ei.Cg-TWis/EiJNcbs (Brachyury mutant) Public Live, Cryo-S Mus Musculus Congenic Spontaneous Mutation JAX JAX# 004591 (f)TBra(het) x (m)B6D2F1; or (f)B6D2F1 x (m)TBra(het) (C57Bl/6J) Black 8 to 12 pups per litter N Global JAX/NCBS/Instem transfer agreements_2017 RS; phenotyped screening:? Public
Tbx6Cre Tg(Tbx6Cre)rsa/Ncbs Public Live, Cryo-S Mus Musculus Tg RS lab (Pasteur Institute Paris) B6D2 ? Tbx6-Cre X B6D2 F1 Black 8-12 pups per litter Y RS lab (Pasteur Institute Paris) RS different lines- Tbx6Cre#5 Tbx6Cre#4 Public
Tbx6YFP Tbx6tm2(HIST1H2BB/EYFP)Pa/Ncbs Public Live, Cryo-S Mus Musculus KO, KI MGI:3798467 ; 043813-JAX (f)Tbx6YFP/+ x (m)B6D2F1 or (f)B6D2F1 x (m)Tbx6YFP/+ Black, grey or coco Y virginia papaioannou, MMRC - JAX RS Public
tdTomatoAi14 B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/JNcbs (tdT or tdTAi14) Public Live, Cryo-E, Cryo-S Mus Musculus Congenic; Gene Trap; Targeted Mutation JAX JAX# 007914 B6/J Homozygote x Homozygote black 2 breeders Global JAX/NCBS/Instem transfer agreements_2017 MMP, SC, AG, GH, ACRC Public
Tie2Cre (Flv) B6.Cg-Tg(Tek-cre)12Flv/JNcbs Public Live, Cryo-S Mus Musculus Congenic, Transgenic (Recombinase-expressing) JAX JAX# 004128 C57BL/6J x Hemizygote OR Hemizygous x C57BL/6J black Y 4 males + 4 females (26-Feb-2009) JAX - NCBS relocation agreements Stock Cryopreserved for Maneesha Inamdar (JNCSAR). Public
Upk3aGCE/+, tdT/+ B6;DBA-Tg(Upk3a-GFP/cre/ERT2)26Amc/J, B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/J (=tdTomatoAi14) / [Ncbs] Public Live, Cryo-S Mus Musculus double - transgenic,Targeted / compound Boston University / JAX components of JAX# 007914 and JAX# 015855 B6/J & DBA Tuesday, February 16, 2016 2F + 2M Global JAX/NCBS/Instem transfer agreements_2017 AG Compound strain imported from Boston University with JAX relocation agreement Public
Vangl2 LPT/LeJNcbs [Vangl2Lp = VANGL planar cell polarity 2 - Loop tail] Public Live, Cryo-S Mus Musculus spontaneous mutation RIKEN-CDB + JAX JAX# 000220??? OR JAX# 013121??? => to clarify by sequencing? mentions CD1 on riken import file??? should be b6J? Monday, January 29, 2018 1 CryoVial (= 63 2-cell embryos) JAX relocation agreement for JAX# 000220 the loop tail mutation of the Vangl2 gene in causing neurodevelopmental defects leading to short, curly tails and spina bifida. There is incomplete penetrance and prenatal and perinatal lethality. Some heterozygous with mild spina bifida survive to adulthood and have bred. Some heterozygous females have closed vaginas. __ JAX Stock#000220 carries a transition point mutation that alters a G to an A at coding nucleotide 1391 (c.1391G>A). This is predicted to alter serine 464 to asparagine (p.S464N) in the encoded protein.Western blot analysis indicates an approximate 80% reduction in protein expression in homozygotes and downward shift in molecular mass that is emulated by dephosphorylation of the wild-type protein. __ JAX stock#013121 is a spontaneous mutation is an A-to-G (T-to-C on forward strand) substitution in the 5' UTR. Public
Vangl2, Sox10-Cre LPT/LeJNcbs, B6;CBA-Tg(Sox10-cre)1Wdr/JNcbs [Vangl2Lp = VANGL planar cell polarity 2 - Loop tail] Public Live Mus Musculus JAX -> NCBS compound of JAX# 000220 (or 013121???) and JAX# 025807 mixed JAX Public
Vangl2-FLOX B6;129-Vangl2tm2.1Mdea/JNcbs Public Live, Cryo-S Mus Musculus targeted mutation JAX -> ACRC JAX#025174 mixed Wednesday, November 27, 2019 JAX These floxed mutant mice possess loxP sites flanking exons 2 and 3 of the Vangl2 gene. This strain may be useful for generating conditional mutations in applications related to planar cell polarity. Public
Vangl2;lgr5 LPT/LeJNcbs;B6.129P2-Lgr5tm1(cre/ERT2)Cle/JNcbs Public Live Mus Musculus Compound(spontaneous mutation + transgenic) RIKEN-CDB + JAX JAX# 000220;JAX#008875 B6J HetXHet Black homozygous lethal the loop tail mutation of the Vangl2 gene Public
Vangl2;Ngn1-457Cre LPT/LeJNcbs [Vangl2Lp = VANGL planar cell polarity 2 - Loop tail]; STOCK Tg(Neurog1-cre)1Jejo/JNcbs Public Live Mus Musculus Compound Vangl2- RIKEN-CDB + JAX--> ACRC, Ngn1-457Cre - JAX --> ACRC Vangl2- JAX# 013121??? or JAX# 000220??? to clarify by sequencing?, Ngn1-457Cre- JAX#012859 Public
WISTAR-15 WISTAR- (2015 NCBS imported) Public Live Rattus norvegicus WT WIS WT X WT Stocks imported to NCBS in 2015 Public
ZO1-EGFP-R26 R26-ZO1-EGFP [Tight Junctions] Public Live Mus Musculus Constutive expressing ZO1-EGFP (Tight junctions) RIKEN-CDB B6/N RIKEN-CDB R26R-ZO1-EGFP (Stock id-#CDB0225K) was crossed with PGK cre (stock id-MGI:2178050). From the F1 litter, mice positive for EGFP and PGK cre was selected and crossed with littermate of the same genotype. In the F2 generation, Mice positive for EGFP and negative for PGK cre was selected. The F2 generation mice is thereafter scientifically named R26-ZO1-EGFP. To avoid confusion in the ACRC facility it is termed as Z01-EGFP-R26. (Details Given by Anubhav (RL lab)) Public