
@article {124444,
	title = {Generation of feeder-independent transgene-free iPSC lines from a young-onset Parkinson{\textquoteright}s disease (YOPD) patient with a homozygous PLA2G6: c.2222G>A (p. Arg741Gln) mutation (NCBSi003-A) and unaffected heterozygous parent (NCBSi004-A).},
	journal = {Stem Cell Res},
	volume = {67},
	year = {2023},
	month = {2023 Jan 24},
	pages = {103033},
	abstract = {<p>Phospholipase A2 group 6 (PLA2G6, iPLA2β or PARK14) gene encodes a calcium-independent group 6 phospholipase A2 enzyme and is associated with young-onset autosomal recessive Parkinson{\textquoteright}s disease (PD). We generated human induced pluripotent stem cell (iPSC) lines from a patient with young-onset PD carrying a homozygous PLA2G6: c.2222G\&gt;A (p. Arg741Gln) mutation (NCBSi003-A) and unaffected heterozygous parent (NCBSi004-A). These iPSC lines will be used for investigating the key molecular signatures of young-onset PD (YOPD), and to understand the predictive phenotypes of the disease.</p>
},
	issn = {1876-7753},
	doi = {10.1016/j.scr.2023.103033},
	author = {Gopurappilly, Renjitha and Musthafa, Thasneem and Sukumaran, Salil and Viswanath, Biju and Hasan, Gaiti}
}
