
@article {155516,
	title = {Reproductive Barriers and Genomic Hotspots of Adaptation During Allopatric Species Divergence.},
	journal = {Mol Ecol},
	year = {2025},
	month = {2025 Mar 04},
	pages = {e17703},
	abstract = {<p class="rtejustify">Theory predicts that in allopatric populations, genomic divergence and reproductive barriers may be driven by random genetic drift and thereby evolve slowly in large populations. However, local adaptation and divergence under selection may also play important roles, which remain poorly characterised. Here, we address three key questions in young allopatric species: (a) How widespread are genomic signatures of adaptive divergence?, (b) What is the functional space along which young sister species show divergence at the genomic level? and (c) How quickly might prezygotic and postzygotic reproductive barriers evolve? Analysis of 82 re-sequenced genomes of the Oriental Papilio polytes species group revealed surprisingly widespread hotspots of intense selection and selective sweeps at hundreds of genes, spanning all chromosomes, rather than divergence only in a few genomic islands. These genes are involved in diverse ecologically important adaptive functions such as wing development, colour patterning, courtship behaviour, mimicry, pheromone synthesis and olfaction, and host plant use and digestion of secondary metabolites, that could contribute to local adaptation and subsequent reproductive isolation. Divergence at such functional genes appeared to have evolved in conjunction with reproductive consequences: behavioural and hybridisation experiments revealed strong assortative mate preference (prezygotic barriers) as well as postzygotic barriers to hybridisation in timespans as short as 1.5 my, indicating that speciation was already complete rather than incipient. Our study thus demonstrates an underappreciated role of intense selection and potential local adaptation in creating genome-wide hotspots of rapid molecular evolution and divergence during differentiation and speciation in young allopatric species.</p>
},
	keywords = {assortative mating; postzygotic reproductive barriers; prezygotic reproductive barriers; selective sweeps; signatures of selection; speciation genomics.},
	issn = {1365-294X},
	doi = {10.1111/mec.17703},
	url = {https://pubmed.ncbi.nlm.nih.gov/40035353/},
	author = {Deshmukh, Riddhi and Baral, Saurav and Kuwalekar, Muktai and Kizhakke, Athulya Girish and Kunte, Krushnamegh}
}
@inbook {103400,
	title = {Evolution of Mimicry Rings as a Window into Community Dynamics},
	booktitle = {ANNUAL REVIEW OF ECOLOGY EVOLUTION AND SYSTEMATICS },
	volume = {52},
	year = {2021},
	pages = {315-341},
	abstract = {<p>Mimicry rings are communities of mimetic organisms that are excellent models for ecological and evolutionary studies because the community composition, the nature of the species interactions, the phenotypes under selection, and the selective agents are well characterized. Here, we review how regional and ecological filtering, density- and frequency-dependent selection, toxicity of prey, and age of mimicry rings shape their assembly. We synthesize findings from theoretical and empirical studies to generate the following hypotheses: (a) the degree of unpalatability and age of mimicry rings increase mimicry ring size and (b) the degree of unpalatability, generalization of the aposematic signal, and availability of alternative prey are positively related to the breadth of the protection umbrella for an aposematic signal and negatively related to the degree of mimetic resemblance. We also provide a phylogenetic framework in which key aspects of mimicry ring diversification may be studied.</p>
},
	issn = {eISSN 1545-2069},
	doi = {10.1146/annurev-ecolsys-012021-024616},
	author = {Kunte, Krushnamegh and Kizhakke, Athulya Girish and Nawge, Viraj and Futuyma, DJ}
}
