
@article {916,
	title = {Fast, Efficient, and Stable Conjugation of Multiple DNA Strands on Colloidal Quantum Dots.},
	journal = {Bioconjug Chem},
	volume = {26},
	year = {2015},
	month = {2015 Aug 19},
	pages = {1582-9},
	abstract = {<p>A novel method for covalent conjugation of DNA to polymer coated quantum dots (QDs) is investigated in detail. This method is fast and efficient: up to 12 DNA strands can be covalently conjugated per QD in optimized reaction conditions. The QD-DNA conjugates can be purified using size exclusion chromatography and the QDs retain high quantum yield and excellent stability after DNA coupling. We explored single-stranded and double-stranded DNA coupling, as well as various lengths. We show that the DNA coupling is most efficient for short (15 mer) single-stranded DNA. The DNA coupling has been performed on QDs emitting at four different wavelengths, as well as on gold nanoparticles, suggesting that this technique can be generalized to a wide range of nanoparticles.</p>
},
	issn = {1520-4812},
	doi = {10.1021/acs.bioconjchem.5b00221},
	author = {Banerjee, Anusuya and Grazon, Chlo{\'e} and Nadal, Brice and Pons, Thomas and Krishnan, Yamuna and Dubertret, Benoit}
}
