
@article {25258,
	title = {Organelle acidification: an ancient cellular leak detector.},
	journal = {BMC Biol},
	volume = {15},
	year = {2017},
	month = {2017 Jun 26},
	pages = {51},
	abstract = {<p>Intracellular membrane-bounded organelles of eukaryotic cells transiently contact the extracellular environment during endocytosis and secretion. Such contacts must be precisely timed to prevent leakage of cargo. I argue that early eukaryotes evolved organelle acidification as a way to detect and prevent leakage.</p>
},
	issn = {1741-7007},
	doi = {10.1186/s12915-017-0395-1},
	author = {Thattai, Mukund}
}
