@article {158501, title = {The primary cilium as a gatekeeper of FGFR2 function}, year = {2025}, abstract = {

In this issue, Nita et al. (https://doi.org/10.1083/jcb.202311030) show that the primary cilium regulates FGFR2 signalling through spatial compartmentalization, enabling selective downstream activation. Disruption of ciliary localization in disease-linked FGFR2 variants highlights the role of the cilium as a signalling gatekeeper in development and disease.

}, doi = {https://doi.org/10.1083/jcb.202505022}, url = {https://rupress.org/jcb/article/224/7/e202505022/278048/The-primary-cilium-as-a-gatekeeper-of-FGFR2}, author = {Raman kaushik and Raj k. Ladher} }