
@article {137340,
	title = {The ubiquitous nanocluster: A molecular scale organizing principle that governs cellular information flow.},
	journal = {Curr Opin Cell Biol},
	volume = {86},
	year = {2024},
	month = {2023 Dec 05},
	pages = {102285},
	abstract = {<p>The language of biology at the scale of the cell is constituted of alphabets represented by biomolecules. These are stitched together in a variety of ways to create meaning. We argue that the phrases of this language are nanoscale molecular assemblies or nano-hubs for the purpose of information flow. At the cell surface information is sensed and processed via membrane receptors, often configured as multimers. These nano-assemblies serve as receiver nano-hubs, which are flexibly configured with additional nano-hubs that we term modifiers and transducers. This framework serves to process information that is transmitted for execution inside the cell. Here, we explore some examples about how nano-hubs are built and how they may contribute to cellular information flow.</p>
},
	issn = {1879-0410},
	doi = {10.1016/j.ceb.2023.102285},
	author = {Garcia-Parajo, Maria F and Mayor, Satyajit}
}
