Advt No.15/2021 : Appointment of a Graduate Trainee in Computational Structural Biology in the laboratory of Dr Shruthi Vishwanath

Essential Qualification and Experience required:

  • Bachelor or Master's in any branch of science or engineering.

  • One (1) year project experience that involves programming in computational biology.

Skills required:

  • Programming experience in Python/C++.

  • Comfortable working in Linux environment.

  • Ability to read and synthesize literature in molecular and cell biology.

Project description:

Computational modeling of 3D structures of large macromolecular assemblies

Three-dimensional structures of large protein assemblies help us understand the mechanistic details of biological processes in the cell. They provide insight into how these molecular machines function, how they are assembled, how they evolved, and how they are regulated. However, such structures are difficult to obtain using any single experimental method. We use computational modeling to determine these structures by combining a variety of experimental data, physical theories, and statistical inference.

Opportunities exist in our group to work on several such assemblies. Three broad areas include (a) assemblies involved in regulating gene expression, including chromatin remodelers (b) assemblies at cell-cell junctions, and (c) cellular machineries involved in cell division such as centriolar and centrosomal protein complexes.

There is a possibility to experimentally validate the in-silico model in our collaborators’ labs.

There are also opportunities to work on improving the modeling methods, using algorithms from statistical inference, for trainees from a more quantitative background.

Number of positions: 2

Minimum % of marks: 75%

Age limit: 40

Salary offered: 25,000 (without CSIR/GATE/equivalent qualification), 31000 + 24% HRA (with CSIR/GATE/equivalent qualification)

How to apply:

Interested applicants are requested to upload their CV and a short statement of research interest based on the topic above (~300 words) on the application portal.

Statements not related to the above topic and incomplete applications missing one of the two documents will not receive any response.

Last date for applying is July 31. Candidates will be contacted and interviewed on a rolling basis till position is filled.

Please note that candidates who have not been selected for interview will not be contacted; we are unable to reply to all inquiries from candidates.

Step to apply:

Step 1: Interested candidates should register ONLINE through the link on our website using a valid email ID.

Step 2: You will receive a user ID and password on your registered email ID.

Step 3: Using your ID and password, you can fill in the application by clicking on “Submit Application”

Step 4: Once you fill in the application, you can SAVE or PREVIEW the application. Please Note: Any corrections should be made before you SAVE the application.

Step 5: After you SAVE, you can submit the application by clicking “SUBMIT”.

Step 6: All essential certificate is proof of your qualification, date of birth, experience, caste, etc. Should be uploaded while submitting the ONLINE application.

Note: Please do NOT send hard copies of applications/documents.

Head, Establishment


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