Instructor: Ramkumar Sambasivan, Tina Mukherjee, Srikala Raghavan, Ravi Muddashetty, Arjun Guha
Time: (W)9:00-10:30 h, (S)10:30-12:00 h
Duration of the course:
11th Feb 2015 to 1st Apr 2015
Days: WS
Credits: 2
Class Room: LH2 (Langra)
Course Outline:

Concepts: Genetic programs and regulation of lineage specification; Mechanisms of self-renewal and differentiation in developmental progenitors (mostly vertebrate development, some aspects using invertebrate models)

I
Blastula:Inner cell mass versus trophectoderm binary fate choice
Embyomic: stem cells- mouse and human embryonic stem cells

II
Gastrulation: signaling cues and transcription factor networks governing 1) A/P axis formation; 2)generation of germ layers (Mesoderm specification)

III
Organogenesis:
1)–Skeletal muscle development: somites,signals and TFs inducing muscle progam, generation of adult skeletal muscle stem cells from developmental progenitor
2) Blood development
3) Introduction to CNS development

IV
Adult stem cells: 1) Satellite cells, the adult muscle stem cells 2) HSCs 3) Skin stem cells

Course Term: Jan Term - 2015
Course Year: 2014/2015