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Bacterial Expressions


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October 22-25, 2013

National Centre for Biological Sciences, TIFR, Bangalore

Conveners: Dr. Aswin Sai Narain Seshasayee, NCBS; Dr. Sandeep Krishna, NCBS; Dr. Deepa Agashe, NCBS

Conference Schedule

Bacteria, besides being agents of infectious disease, are the predominant form of free-living life on Earth. Some bacteria live in stable environments, such as in a symbiotic relationship with a host; others can live across multiple habitats each presenting its own set of nutrients and adversaries. This leads to the following:

 1. Any bacterium should code for only those genes that would allow it to make optimal use of the conditions prevailing in its set of habitats.

 

2. Regulation is critical especially to organisms that traverse multiple types of habitats, to ensure that only those genes required at any given time point are expressed.

Recent studies have indicated that regulation of gene expression at the level of transcription is complex even in relatively simple bacteria. This involves a variety of players operating at distinct levels.

The DNA sequence itself is a determinant of gene expression. Over very short time-scales, this is static and does not always allow dynamic responses to changing conditions; however, the local and the global structure of the chromosome is dynamic and can respond to perturbations and affect DNA transactions including replication and transcription. On top of this are a group of global transcription factors and nucleoid-associated proteins, which affect the expression of large numbers of genes in diverse ways. Numerous small RNAs have also been implicated in bacterial stress responses and virulence. Further, the activity of each of these players is regulated by metabolites and small signaling molecules.

This meeting brings together internationally recognized scientists whose continuing contributions have advanced the field of bacterial molecular biology to a great extent. These scientists represent the employment of a wide variety of physical, mathematical, biochemical and genetic methods towards understanding gene expression in bacteria.


Sponsors:

DBT   

              LADY TATA MEMORIAL TRUST

 

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Embo lecture: Jörg Vogel, Institute of Molecular Infection Biology, University of Würzburg, Germany

 

Plenary talks: 

1. Steven Busby, School of Biosciences, University of Birmingham

2. Charles Dorman, Department of Microbiology, Trinity College, Dublin

3. Sankar Adhya, Center for Cancer Research, National Cancer Institute, Bethesda

 

Speakers: 

 

Name

Affiliation

David Grainger 

School of Biosciences, University of Birmingham

Georgi Muskhelishvili

Jacobs University, Bremen

Joel Gaffe 

Institut Jean Roget, Universite Joseph Fourier, Grenoble

Dipankar Chatterji

Molecular Biophysics Unit, Indian Institute of Science, Bangalore

Ian Dodd

School of Molecular and Biomedical Science, University of Adelaide

Gillian Fraser

Department of Pathology, University ofCambridge

Kim Sneppen

Niels Bohr Institute, Copenhagen

Szabolcs Semsey

Niels Bohr Institute, Copenhagen

S. Mahadevan

Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore

Marco Cosentino Lagomarsino

Universite Pierre et Marie Curie

Bianca Sclavi

Ecole Normale Superieure, Cachan

J. Gowrishankar

Laboratory of Bacterial Genetics, Centre for DNA Fingerprinting and Diagnostics, Hyderabad

Ana Rita Brochado

EMBL Heidelberg 

Sunish Radhakrishnan

School of Biology, Indian Institute of Science Education and Research, Thiruvananthapuram

Supreet Saini

Indian Institute of Technology, Mumbai

Krishnan Sankaran

Anna University

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 Last date for registration and abstract submission: July 10, 2013

 Selected participants will be informed of the decision on: August 1, 2013

 

 

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We invite applications from students, post-docs and junior faculty. There is no registration fee.

If you would like us to arrange for your accommodation, please indicate this in the form below. Note that this will be shared accommodation and will incur a charge of Rs. 500 per person per day. If you do not indicate that you need accommodation, you will have to make your own arrangements for this.

This application form will be open till 10th July 2013, 17:00 hrs, Indian Standard Time. The result of your application will be declared by 1st August 2013.

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expressions@ncbs.res.in